The vertebrate control of locomotion involves all levels of the nervous system from cortex to
the spinal cord. Here, we aim to cover all main aspects of this complex behavior, from the …

Since no approved therapies to restore mobility and sensation following spinal cord injury
(SCI) currently exist, a better understanding of the cellular and molecular mechanisms …

Spinal sensorimotor networks that are functionally disconnected from the brain because of
spinal cord injury (SCI) can be facilitated via epidural electrical stimulation (EES) to restore …

Previously, we reported that one individual who had a motor complete, but sensory
incomplete spinal cord injury regained voluntary movement after 7 months of epidural …

Background Repeated periods of stimulation of the spinal cord and training increased the
ability to control movement in animal models of spinal cord injury. We hypothesised that …

After an initial period of recovery, human neurological injury has long been thought to be
static. In order to improve quality of life for those suffering from stroke, spinal cord injury, or …

Rehabilitative exercise in humans with spinal cord injury aims to engage residual neural
networks to improve functional recovery. We hypothesized that exercise combined with non …

Background: Powered exoskeletons have been demonstrated as being safe for persons with
spinal cord injury (SCI), but little is known about how users learn to manage these devices …

Spinal cord injury (SCI) commonly results in permanent loss of motor, sensory, and
autonomic function. Recent clinical studies have shown that epidural spinal cord stimulation …

One of the big challenges in neuroscience that remains to be understood is why the central
nervous system is not able to regenerate to the extent that the peripheral nervous system …