Parkinson's disease (PD) is a neurodegenerative disease characterized by a progressive
loss of dopaminergic neurons from the nigrostriatal pathway, formation of Lewy bodies, and …

Neurodegeneration leading to Parkinson's disease (PD) and Alzheimer's disease (AD) has
become a major health burden globally. Current treatments mainly target controlling …

The endocannabinoid system (ECS) is composed of the endocannabinoid ligands
anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors …

Significance: Redox imbalance may lead to overproduction of reactive oxygen and nitrogen
species (ROS/RNS) and subsequent oxidative tissue damage, which is a critical event in the …

The omega-3 fatty acid ethanolamides, docosahexaenoyl ethanolamide (DHEA) and
eicosapentaenoyl ethanolamide (EPEA), displayed greater anti-proliferative potency than …

Pharmacomodulation of membrane channels is an essential topic in the study of
physiological conditions and disease status. Transient receptor potential (TRP) channels are …

The endocannabinoid system (ECS) consists of endogenous cannabinoids, their receptors,
and metabolic enzymes that play a critical homeostatic role in modulating polyunsaturated …

The endocannabinoid system (ECS) and reactive oxygen species (ROS) constitute two key
cellular signalling systems that participate in the modulation of diverse cellular functions …

Cannabinoids-endocannaboids are possible preventatives of common diseases including
cancers. Cannabinoid receptors (CB1/2, TRPV1) are central components of the system …

Cannabinoids have been widely reported to have neuroprotective properties in vitro and in
vivo. In this study we compared the effects of CB1 and CB2 receptor-selective ligands, the …