Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Hydrogen sulfide and cell signaling

L Li, P Rose, PK Moore - Annual review of pharmacology and …, 2011 - annualreviews.org
Hydrogen sulfide (H2S) is a gaseous mediator synthesized from cysteine by cystathionine γ
lyase (CSE) and other naturally occurring enzymes. Pharmacological experiments using …

Hydrogen sulfide signaling in the gastrointestinal tract

DR Linden - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: The current literature regarding the effects of the gaseous signal molecule
hydrogen sulfide (H2S) in the gastrointestinal system is reviewed. Bacterial, host and …

[HTML][HTML] Intestinal microbiota in pathophysiology and management of irritable bowel syndrome

KN Lee, OY Lee - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Irritable bowel syndrome (IBS) is a functional bowel disorder without any structural or
metabolic abnormalities that sufficiently explain the symptoms, which include abdominal …

The therapeutic potential of hydrogen sulfide: separating hype from hope

KR Olson - American Journal of Physiology-Regulatory …, 2011 - journals.physiology.org
Hydrogen sulfide (H2S) has become the hot new signaling molecule that seemingly affects
all organ systems and biological processes in which it has been investigated. It has also …

Emerging role of hydrogen sulfide in colonic physiology and pathophysiology

M Medani, D Collins, NG Docherty… - Inflammatory Bowel …, 2011 - academic.oup.com
Almost 50% of patients with inflammatory bowel disease (IBD) will undergo surgery for their
disease at some stage of its clinical course. Complications seen following surgery may occur …

Role of hydrogen sulfide in health and disease

YQ Jin, H Yuan, YF Liu, YW Zhu, Y Wang… - MedComm, 2024 - Wiley Online Library
In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent
years, with increased research, we have discovered that H2S can act as an endogenous …

Beyond phylotyping: understanding the impact of gut microbiota on host biology

CS Reigstad, PC Kashyap - Neurogastroenterology & Motility, 2013 - Wiley Online Library
Background Microbial constituents of the gut microbiome interact with each other and the
host to alter the luminal environment and impact development, motility, and homeostasis of …

A New Slow Releasing, H2S Generating Compound, GYY4137 Relaxes Spontaneous and Oxytocin-Stimulated Contractions of Human and Rat Pregnant …

H Robinson, S Wray - 2012 - journals.plos.org
Better tocolytics are required to help prevent preterm labour. The gaseotransmitter Hydrogen
sulphide (H2S) has been shown to reduce myometrial contractility and thus is of potential …

Hydrogen sulphide as a signalling molecule regulating physiopathological processes in gastrointestinal motility

M Jimenez, V Gil, M Martinez‐Cutillas… - British Journal of …, 2017 - Wiley Online Library
The biology of H2S is a still developing area of research and several biological functions
have been recently attributed to this gaseous molecule in many physiological systems …