The introduction of duplex Doppler ultrasound almost half a century ago signified a
revolutionary advance in the ability to assess limb blood flow in humans. It is now widely …

As dysfunction of the vascular system is an early, modifiable step in the progression of many
cardiovascular diseases, there is demand for methods to monitor the health of the vascular …

Skeletal muscle dysfunction after critical illness, defined as ICU-acquired weakness (ICU-
AW), is a complex and multifactorial syndrome that contributes significantly to long-term …

Passive exercise/movement has a long history in both medicine and physiology. Early
clinical applications of passive exercise/movement utilized pneumatic and direct limb …

Objective Sepsis is a major cause of mortality among critically ill patients in the intensive
care unit (ICU). Alterations in serum amyloid A (SAA) and nitric oxide (NO) levels have been …

There is accumulating evidence for both peripheral vascular dysfunction and impaired
functional capacity in patients with heart failure with a preserved ejection fraction (HFpEF) …

Passive leg movement (PLM)-induced hyperemia is a novel approach to assess vascular
function, with a potential clinical role. However, in some instances, the varying chronotropic …

While there is emerging evidence of peripheral microvascular dysfunction in patients with
heart failure with preserved ejection fraction (HFpEF) that may be related to systemic …

New Findings What is the central question of this study? Use of the passive leg movement
(PLM) test, a non‐invasive assessment of microvascular function, is on the rise. However …

Vegetarians (VEG) are reported to have lower body weight, blood pressure (BP), and
cardiovascular disease (CVD) risk compared with omnivores (OMN), yet the mechanisms …