Somatostatin: Linking Cognition and Alzheimer Disease to Therapeutic Targeting

KE Sandoval, KA Witt - Pharmacological Reviews, 2024 - pharmrev.aspetjournals.org
Over 4 decades of research support the link between Alzheimer disease (AD) and
somatostatin [somatotropin-releasing inhibitory factor (SRIF)]. SRIF and SRIF-expressing …

Somatostatin and the pathophysiology of Alzheimer's disease

VN Almeida - Ageing Research Reviews, 2024 - Elsevier
Among the central features of Alzheimer's disease (AD) progression are altered levels of the
neuropeptide somatostatin (SST), and the colocalisation of SST-positive interneurons (SST …

Language dysfunction correlates with cognitive impairments in older adults without dementia mediated by amyloid pathology

C Xiang, W Ai, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Previous studies have explored the application of non-invasive biomarkers of
language dysfunction for the early detection of Alzheimer's disease (AD). However …

“I don't know who you are”: anomia for people's names in Alzheimer's disease

V Gomes, T Simón, M Lázaro - Aging, Neuropsychology, and …, 2024 - Taylor & Francis
It is well known that difficulty in the retrieval of people's names is an early symptom of
Alzheimer's Disease Dementia (ADD), but there is a controversy about the nature of this …

[HTML][HTML] Breaking the barriers in management of Alzheimer's disease through cationic nanoformulation: A review

A Puri, P Mohite, S Khan, S Singh - Results in Chemistry, 2024 - Elsevier
Neurodegenerative Alzheimer's disease (AD) leads to cognitive and behavioral decline. The
current crop of FDA-approved treatments for AD can only reduce symptoms and postpone …

Differences in electroencephalography oscillations between normal aging and mild cognitive impairment during semantic memory retrieval

HS Chiang, EA Lydon, MA Kraut… - European Journal of …, 2023 - Wiley Online Library
Semantic memory remains relatively stable with normal cognitive aging and declines in
early stages of neurodegenerative disease. We measured electroencephalography (EEG) …

[HTML][HTML] Neurodynamics of “cognitive conflict”: Theory and illustrative case study

J Chládek, P Bob, R Roman, I Rektor, M Macek… - Medical …, 2023 - Elsevier
Cognitive interference as a representation of experienced “intrapsychic conflict” according to
some findings might be attributed to competitive neural assemblies interacting during …

The Ability to Use Contextual Information in Object and Scene Recognition in Patients with Mild Cognitive Impairment

Y Wang, K Yang, P Fu, X Zheng… - Journal of …, 2023 - content.iospress.com
Background: The ability to understand and make use of object-scene relationships are
critical for object and scene recognition. Objective: The current study assessed whether …

Characteristics and Potential Neural Substrates of Encoding and Retrieval During Memory Binding in Amnestic Mild Cognitive Impairment

Y Zheng, T Li, T Xie, Y Zhang, Y Liu… - Journal of …, 2023 - content.iospress.com
Background: Whether encoding or retrieval failure contributes to memory binding deficit in
amnestic mild cognitive impairment (aMCI) has not been elucidated. Also, the potential brain …

The Semantic Association Test (SAT): normative data from healthy Italian participants and a validation study in aphasic patients

E Banco, L Veronelli, M Briguglio, C Luzzatti… - Neurological …, 2023 - Springer
Abstract The Semantic Association Test assesses several aspects of Semantic Memory
(Categorical, Encyclopedic, Functional, and Visual Encyclopedic associations: CAs, EAs …