The liver is an immune organ that plays a vital role in the detection, capture, and clearance
of pathogens and foreign antigens that invade the human body. During acute and chronic …

Background & Aims Chronic viral infections present serious public health challenges;
however, direct-acting antivirals (DAAs) are now able to cure nearly all patients infected with …

The human liver is a complex organ made up of multiple specialized cell types that carry out
key physiological functions. An incomplete understanding of liver biology limits our ability to …

In hepatocellular carcinoma (HCC), γδ T cells participate in mediating the anti‐tumour
response and are linked with a positive prognosis. However, these cells can become pro …

Abstract Background and Aims: Chronic liver disease due to metabolic dysfunction–
associated steatohepatitis (MASH) is a rapidly increasing global epidemic. MASH …

Diabetic nephropathy (DN) is a common secondary kidney disease. Immune and
inflammatory responses play an influential role in the development of DN. This study aims to …

Chronic hepatitis C virus infection is a major cause of mortality due to liver cirrhosis globally.
Despite the advances in recent therapeutic strategies, there is yet a high burden of HCV …

The COVID-19 pandemic has prompted a quest to understand why certain individuals
remain uninfected or asymptomatic despite repetitive exposure to SARS-CoV-2. Here, we …

To identify T cell subsets associated with control of tuberculosis, single-cell transcriptome
and T cell receptor sequencing were performed on total T cells from patients with …

The development of direct-acting antivirals (DAAs) against hepatitis C virus (HCV) has
revolutionized the management of this pathology, as their use allows viral elimination in a …