The scientific interest in irisin, a myokine discovered in 2012, has grown exponentially in
recent years. Irisin, which is mainly produced in skeletal muscle, influences the browning …

Osteoarthritis is a chronic degenerative musculoskeletal disease characterized by
pathological changes in joint structures along with the incidence of which increases with …

Irisin, a myokine secreted by muscle during physical exercise, is known to have biological
activities in different cell types. Chondrocyte inflammation and pyroptosis have been shown …

Background Adipocytokines, which are secreted by the adipose tissue, contribute to the
pathogenesis of obesity-related complications. To evaluate this assumption, we investigated …

Irisin is a muscle factor discovered in 2012 that plays an important role in many tissues,
including bone. Eight years since its discovery, there are still many controversies regarding …

In the present study, we investigated the effects of high-intensity interval training (HIIT)
versus moderate-intensity continuous training (MICT) on irisin and expression of myogenic …

Irisin, a recently identified myokine, plays an important physiological role in modulating
energy homeostasis. However, the role of irisin in cardiac function during exercise has not …

Background: Regular exercise is an effective non-pharmacological therapy for treatment and
prevention of cardiovascular disease (CVD). The therapeutic benefits of exercise are …

Background Omentin-1 has been acknowledged as an anti-inflammatory and insulin-
sensitizing marker, which is mainly expressed in adipose tissue. Exercise training is a …

Background Irisin and betatrophin are involved in insulin resistance. We investigated the
effects of aerobic and resistance exercise (AE/RE) and de-training (cessation of the training …