Hepatocytes exert pivotal roles in metabolism, protein synthesis and detoxification. Non-
parenchymal liver cells (NPCs), largely comprising macrophages, dendritic cells, hepatic …

The Helios protein (encoded by the IKZF2 gene) is a member of the Ikaros transcription
family and it has recently been proposed as a promising biomarker for systemic lupus …

Dendritic cells (DCs) are essential orchestrators of immune responses and represent
potential targets for immunomodulation in autoimmune diseases. Human amniotic fluid …

Autoimmune diseases are diseases in which the regulatory mechanisms of the immune
response are disturbed. As a result, the body loses self‐tolerance. Since one of the main …

Systemic lupus erythematosus (SLE) is an autoimmune disease in which defective T cells,
immune complex deposition and other immune system alterations contribute to pathological …

Background Increasing evidence suggests that multipotent mesenchymal stem/stromal cells
(MSCs) are a promising intervention strategy in treating autoimmune inflammatory diseases …

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease reflecting an
imbalance between regulatory and effector immune responses. With the rapid development …

It is well known that dendritic cell (DC) activation and function are underpinned by profound
changes in cellular metabolism. Several studies indicate that the ability of DCs to promote …

Dendritic cells (DCs) play a crucial role in promoting tolerance through priming of regulatory
T cells (Treg). Several studies indicate DC tolerogenicity is dependent on catabolic …