This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Sleep is critical for diverse aspects of brain function in animals ranging from invertebrates to
humans. Powerful genetic tools in the fruit fly Drosophila melanogaster have identified—at …

The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

We define the chemoconnectome (CCT) as the entire set of neurotransmitters,
neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an …

Little is known about the ability of Drosophila circadian neurons to promote sleep. Here we
show, using optogenetic manipulation and video recording, that a subset of dorsal clock …

Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

The circadian clock and its output pathways play a pivotal role in optimizing daily processes.
To obtain insights into how diverse rhythmic physiology and behaviors are orchestrated, we …

Assigning behavioral functions to neural structures has long been a central goal in
neuroscience and is a necessary first step toward a circuit-level understanding of how the …

Circadian clocks regulate membrane excitability in master pacemaker neurons to control
daily rhythms of sleep and wake. Here, we find that two distinctly timed electrical drives …

The Drosophila core circadian circuit contains distinct groups of interacting neurons that give
rise to diurnal sleep-wake patterns. Previous work showed that a subset of dorsal neurons 1 …