Disease detection and management via single nanopore-based sensors

JE Reiner, A Balijepalli, JWF Robertson… - Chemical …, 2012 - ACS Publications
As nanometer-scale portals in biological membranes, protein ionic channels act as
gatekeepers, controlling the traffic of ions and macromolecules into and out of cells …

Slowing and controlling the translocation of DNA in a solid-state nanopore

B Luan, G Stolovitzky, G Martyna - Nanoscale, 2012 - pubs.rsc.org
DNA sequencing methods based on nanopores could potentially represent a low-cost and
high-throughput pathway to practical genomics, by replacing current sequencing methods …

Stacked Graphene-Al2O3 Nanopore Sensors for Sensitive Detection of DNA and DNA–Protein Complexes

BM Venkatesan, D Estrada, S Banerjee, X Jin… - ACS …, 2012 - ACS Publications
We report the development of a multilayered graphene-Al2O3 nanopore platform for the
sensitive detection of DNA and DNA–protein complexes. Graphene-Al2O3 nanolaminate …

Control of DNA capture by nanofluidic transistors

KH Paik, Y Liu, V Tabard-Cossa, MJ Waugh… - ACS …, 2012 - ACS Publications
We report the use of an array of electrically gated∼ 200 nm solid-state pores as nanofluidic
transistors to manipulate the capture and passage of DNA. The devices are capable of …

New electrochemical methods

C Batchelor-McAuley, EJF Dickinson, NV Rees… - Analytical …, 2012 - ACS Publications
This review is predominantly focused upon articles dating from 2009 to 2011. The authors
have attempted to highlight areas of recent and significant development, with the aim of …

Fabrication and characterization of nanopores with insulated transverse nanoelectrodes for DNA sensing in salt solution

K Healy, V Ray, LJ Willis, N Peterman, J Bartel… - …, 2012 - Wiley Online Library
We report on the fabrication, simulation, and characterization of insulated nanoelectrodes
aligned with nanopores in low‐capacitance silicon nitride membrane chips. We are …

Dynamics of DNA translocation in a solid-state nanopore immersed in aqueous glycerol

B Luan, D Wang, R Zhou, S Harrer, H Peng… - …, 2012 - iopscience.iop.org
Nanopore-based technologies have attracted much attention recently for their promising use
in low-cost and high-throughput genome sequencing. To achieve single-base resolution of …

DNA sequence using multiple metal layer structure with different organic coatings forming different transient bondings to DNA

A Afzali-Ardakani, S Harrer, B Luan, H Peng… - US Patent …, 2015 - Google Patents
A nanodevice includes a reservoir filled with conductive fluid and a membrane separating
the reservoir. A nanopore is formed through the membrane having electrode layers …

Long passage times of short ssDNA molecules through metallized nanopores fabricated by controlled breakdown

H Kwok, M Waugh, J Bustamante… - Advanced Functional …, 2014 - Wiley Online Library
The fabrication of individual nanopores in metallized dielectric membranes using controlled
breakdown directly in solution is described. Nanopores as small as 1.5‐nm in diameter are …

Functionally switchable self-assembled coating compound for controlling translocation of molecule through nanopores

A Afzali-Ardakani, S Harrer, B Luan, H Peng… - US Patent …, 2018 - Google Patents
A technique for a nanodevice is provided. The nanodevice includes a fluidic cell, and a
membrane dividing the fluidic cell. A nanopore is formed through the membrane, and the …