Many questions have been posed about acquired immunodeficiency syndrome (AIDS)
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …

The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …

The principles of magnetic separation aided by antibodies or other specific binding
molecules have been used for isolation of specific viable whole organisms, antigens, or …

▪ Abstract In the absence of antiretroviral treatment, HIV-1 establishes a chronic, progressive
infection of the human immune system that invariably, over the course of years, leads to its …

▪ Abstract Human immunodeficiency virus-1 (HIV-1) is usually transmitted through sexual
contact and in the very early stages of infection establishes a persistent infection in …

HIV-1 replication in the central nervous system (CNS) is typically limited by the availability of
target cells. HIV-1 variants that are transmitted and dominate the early stages of infection …

While CD4+ T cell depletion is key to disease progression in people living with HIV and SIV-
infected macaques, the mechanisms underlying this depletion remain incompletely …

In immature thymocytes, T cell receptor for antigen (TCR) mobilization leads to an active T
cell suicide process, apoptosis, which is involved in the selection of the T cell repertoire. We …

Neither the number of HIV-1 proviruses within individual infected cells in HIV-1–infected
patients nor their genetic relatedness within individual infected cells and between cells and …