Five-decade update on chemopreventive and other pharmacological potential of Kurarinone: a natural flavanone
In the present article we present an update on the role of chemoprevention and other
pharmacological activities reported on kurarinone, a natural flavanone (from 1970 to 2021) …
pharmacological activities reported on kurarinone, a natural flavanone (from 1970 to 2021) …
Mechanistic insights on burdock (Arctium lappa L.) extract effects on diabetes mellitus
SC Mondal, JB Eun - Food Science and Biotechnology, 2022 - Springer
Diabetes mellitus (DM) type 2 is amongst the most common chronic diseases, being
responsible for various problems in humans and contributing to increased mortality rates …
responsible for various problems in humans and contributing to increased mortality rates …
Identification of natural inhibitors against SARS-CoV-2 drugable targets using molecular docking, molecular dynamics simulation, and MM-PBSA approach
PP Kushwaha, AK Singh, T Bansal, A Yadav… - Frontiers in cellular …, 2021 - frontiersin.org
The present study explores the SARS-CoV-2 drugable target inhibition efficacy of
phytochemicals from Indian medicinal plants using molecular docking, molecular dynamics …
phytochemicals from Indian medicinal plants using molecular docking, molecular dynamics …
Evaluation of antidiabetic activity of dietary phenolic compound chlorogenic acid in streptozotocin induced diabetic rats: Molecular docking, molecular dynamics, in …
Background Chlorogenic acid is amongst the well-known polyphenolic compounds being
used in human food and beverages. Its presence has been reported in tea leaves, roasted …
used in human food and beverages. Its presence has been reported in tea leaves, roasted …
[HTML][HTML] Current therapeutic modalities and chemopreventive role of natural products in liver cancer: Progress and promise
Liver cancer is a severe concern for public health officials since the clinical cases are
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …
increasing each year, with an estimated 5-year survival rate of 30%–35% after diagnosis …
Targeting breast cancer-derived stem cells by dietary phytochemicals: a strategy for cancer prevention and treatment
KS Prajapati, S Gupta, S Kumar - Cancers, 2022 - mdpi.com
Simple Summary Luminal A subtype breast cancer is the most prevalent form of breast
malignancy with frequent diagnosis in women. Breast cancer stem cells (BCSCs) are a rare …
malignancy with frequent diagnosis in women. Breast cancer stem cells (BCSCs) are a rare …
Withaniasomnifera phytochemicals possess SARS-CoV-2 RdRp and human TMPRSS2 protein binding potential
KS Prajapati, AK Singh, PP Kushwaha, M Shuaib… - Vegetos, 2023 - Springer
Abstract Coronavirus disease-19 (COVID-19) pandemic caused by severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2) has infected approximately 26 million people and …
syndrome-coronavirus-2 (SARS-CoV-2) has infected approximately 26 million people and …
Livogrit prevents methionine-cystine deficiency induced nonalcoholic steatohepatitis by modulation of steatosis and oxidative stress in human hepatocyte-derived …
A Balkrishna, V Gohel, P Kumari, M Manik… - …, 2022 - Taylor & Francis
The prevalence of nonalcoholic steatohepatitis (NASH), characterized by fatty liver, oxidative
injury, and inflammation, has considerably increased in the recent years. Due to the …
injury, and inflammation, has considerably increased in the recent years. Due to the …
Identification of cancer stemness related miRNA (s) using integrated bioinformatics analysis and in vitro validation
The stemness property of cells allows them to sustain their lineage, differentiation,
proliferation, and regeneration. MicroRNAs are small non-coding RNAs known to regulate …
proliferation, and regeneration. MicroRNAs are small non-coding RNAs known to regulate …
Hesperidin potentially interacts with the catalytic site of gamma-secretase and modifies notch sensitive genes and cancer stemness marker expression in colon cancer …
Gamma secretase (GS) produces Notch Intracellular Domain (NICD) by trans-membrane
cleavage of notch receptor. The NICD enters the nucleus and activates the notch signaling …
cleavage of notch receptor. The NICD enters the nucleus and activates the notch signaling …