Point-of-care hemostatic testing in cardiac surgery: a stepped-wedge clustered randomized controlled trial

K Karkouti, J Callum, DN Wijeysundera, V Rao… - Circulation, 2016 - Am Heart Assoc
Background: Cardiac surgery is frequently complicated by coagulopathic bleeding that is
difficult to optimally manage using standard hemostatic testing. We hypothesized that point …

Cold-stored platelets for acute bleeding in cardiac surgical patients: a narrative review

J Lu, K Karkouti, M Peer, M Englesakis… - Canadian Journal of …, 2023 - Springer
Purpose Cold-stored platelets (CSP) are an increasingly active topic of international
research. They are maintained at 1–6° C, in contrast to standard room-temperature platelets …

Refrigerated storage of platelets initiates changes in platelet surface marker expression and localization of intracellular proteins

B Wood, MP Padula, DC Marks, L Johnson - Transfusion, 2016 - Wiley Online Library
BACKGROUND Platelets (PLTs) are currently stored at room temperature (22° C), which
limits their shelf life, primarily due to the risk of bacterial growth. Alternatives to room …

Characterization of biologic response modifiers in the supernatant of conventional, refrigerated, and cryopreserved platelets

L Johnson, S Tan, E Jenkins, B Wood, DC Marks - Transfusion, 2018 - Wiley Online Library
BACKGROUND Alternatives to room temperature storage of platelets (PLTs) are of interest
to support blood banking logistics. The aim of this study was to compare the presence of …

Blood-borne pathogens: a Canadian Blood Services Centre for innovation symposium

GM Walsh, AW Shih, Z Solh, M Golder… - Transfusion medicine …, 2016 - Elsevier
Testing donations for pathogens and deferring selected blood donors have reduced the risk
of transmission of known pathogens by transfusion to extremely low levels in most …

COVID‐19 vaccine humoral response in frequent platelet donors with plateletpheresis‐associated lymphopenia

AE Laumaea, A Lewin, D Chatterjee, L Marchitto… - …, 2022 - Wiley Online Library
Background Plateletpheresis involves platelet separation and collection from whole blood
while other blood cells are returned to the donor. Because platelets are replaced faster than …

Frequency of human platelet antigens (HPA)‐1,‐2,‐5 and‐15 in Brazilian blood donors and establishment of a panel of HPA‐typed donors

CMB Mangerona, FB Garcia… - Transfusion …, 2015 - Wiley Online Library
Objectives The aim of this study is to keep a record of regular human platelet antigens (HPA)‐
typed blood donors and to compare their allele frequencies with those reported in other …

Plasma and plasma protein product transfusion: a canadian blood services centre for innovation symposium

MP Zeller, KS Al-Habsi, M Golder, GM Walsh… - Transfusion Medicine …, 2015 - Elsevier
Plasma obtained via whole blood donation processing or via apheresis technology can
either be transfused directly to patients or pooled and fractionated into plasma protein …

Intersecting worlds of transfusion and transplantation medicine: an international symposium organized by the Canadian blood services centre for innovation

KM Hodgkinson, J Kiernan, AW Shih, Z Solh… - Transfusion Medicine …, 2017 - Elsevier
The principal theme of the symposium was centered on how the world of regenerative
medicine intersects with that of transfusion medicine, with a particular focus on …

Evaluation of Changes in platelet level and influenced factors in patients with thrombocytopenia

B Alikiaii, S Dashti - Journal of Isfahan Medical School, 2018 - jims.mui.ac.ir
Background: Hemostasis is a hemodynamic process in which the platelet play a major role.
Platelet transfusion is one of the effective treatments in patients with thrombocytopenia …