Sjögren's syndrome (SS) is a prototype autoimmune disease characterized by oral and ocular mucosal dryness following chronic inflammation of salivary and lachrymal glands …
J Wess, RM Eglen, D Gautam - Nature reviews Drug discovery, 2007 - nature.com
Muscarinic acetylcholine receptors (mAChRs), M1–M5, regulate the activity of numerous fundamental central and peripheral functions. The lack of small-molecule ligands that can …
Sjogren's syndrome (SS) is a slowly progressing autoimmune disease, affecting predominantly middle-aged women, with a female to male ratio reaching 9: 1. It is …
• Mild chronic renal compromise34 continued association with antibodies against neuropeptides. 42 Increased rates of neuroticism, psychoticism, obsessiveness …
R Giacomelli, A Afeltra, A Alunno, C Baldini… - Autoimmunity …, 2017 - Elsevier
Autoimmune diseases are a complex set of diseases characterized by immune system activation and, although many progresses have been done in the last 15 years, several …
Context: Systemic autoimmune and inflammatory diseases often manifest oral lesions in their earliest stages, and early diagnosis, which may be spurred by a dental examination, is …
SA Mathews, BT Kurien… - Journal of dental …, 2008 - journals.sagepub.com
Sjögren's syndrome is a common autoimmune rheumatic disease. The most common symptoms of Sjögren's syndrome are extreme tiredness, along with dry eyes …
PP Pavlakis, H Alexopoulos, ML Kosmidis… - Journal of …, 2012 - Elsevier
Sjögren's syndrome is a systemic autoimmune disease that, apart from exocrine glands, may affect every organ or system. Involvement of different sections of the peripheral nervous …
Sjögren's syndrome is a chronic inflammatory process that primarily involves the exocrine glands. Its clinical manifestations range from autoimmune exocrinopathy to extraglandular …