Rapid, point‐of‐care antigen tests for diagnosis of SARS‐CoV‐2 infection

J Dinnes, P Sharma, S Berhane… - Cochrane database …, 2022 - cochranelibrary.com
Background Accurate rapid diagnostic tests for SARS‐CoV‐2 infection would be a useful
tool to help manage the COVID‐19 pandemic. Testing strategies that use rapid antigen tests …

[HTML][HTML] Accuracy of novel antigen rapid diagnostics for SARS-CoV-2: A living systematic review and meta-analysis

LE Brümmer, S Katzenschlager, M Gaeddert… - PLoS …, 2021 - journals.plos.org
Background SARS-CoV-2 antigen rapid diagnostic tests (Ag-RDTs) are increasingly being
integrated in testing strategies around the world. Studies of the Ag-RDTs have shown …

[HTML][HTML] N-protein presents early in blood, dried blood and saliva during asymptomatic and symptomatic SARS-CoV-2 infection

D Shan, JM Johnson, SC Fernandes, H Suib… - Nature …, 2021 - nature.com
The COVID-19 pandemic continues to have an unprecedented impact on societies and
economies worldwide. There remains an ongoing need for high-performance SARS-CoV-2 …

[HTML][HTML] Time series analysis and mechanistic modelling of heterogeneity and sero-reversion in antibody responses to mild SARS‑CoV-2 infection

C Manisty, TA Treibel, M Jensen, A Semper, G Joy… - …, 2021 - thelancet.com
Background SARS-CoV-2 serology is used to identify prior infection at individual and at
population level. Extended longitudinal studies with multi-timepoint sampling to evaluate …

Diagnostic value of nucleocapsid protein in blood for SARS-CoV-2 infection

Y Zhang, CM Ong, C Yun, W Mo, JD Whitman… - Clinical …, 2022 - academic.oup.com
Background Biomarkers have been widely explored for coronavirus disease 2019
diagnosis. Both viral RNA or antigens (Ag) in the respiratory system and antibodies (Ab) in …

SARS-CoV-2 nucleocapsid plasma antigen for diagnosis and monitoring of COVID-19

H Wang, CA Hogan, M Verghese, D Solis… - Clinical …, 2022 - academic.oup.com
Background Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
nucleocapsid antigen in blood has been described, but the diagnostic and prognostic role of …

[HTML][HTML] Plasma SARS-CoV-2 nucleocapsid antigen levels are associated with progression to severe disease in hospitalized COVID-19

KD Wick, A Leligdowicz, A Willmore, SA Carrillo… - Critical Care, 2022 - Springer
Abstract Background Studies quantifying SARS-CoV-2 have focused on upper respiratory
tract or plasma viral RNA with inconsistent association with clinical outcomes. The …

[HTML][HTML] Cellular immunity—the key to long-term protection in individuals recovered from SARS-CoV-2 and after vaccination

D Primorac, P Brlek, V Matišić, V Molnar, K Vrdoljak… - Vaccines, 2022 - mdpi.com
Previous clinical and epidemiological studies have shown that over time antibody titers
decrease, and they do not provide long-term mucosa protection against SARS-CoV-2 …

[HTML][HTML] An update on detection technologies for SARS-CoV-2 variants of concern

W Jiang, W Ji, Y Zhang, Y Xie, S Chen, Y Jin, G Duan - Viruses, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is responsible for the
global epidemic of Coronavirus Disease 2019 (COVID-19), with a significant impact on the …

Low anti‐SARS‐CoV‐2 S antibody levels predict increased mortality and dissemination of viral components in the blood of critical COVID‐19 patients

M Martin‐Vicente, R Almansa, I Martínez… - Journal of internal …, 2022 - Wiley Online Library
Abstract Background Anti‐SARS‐CoV‐2 S antibodies prevent viral replication. Critically ill
COVID‐19 patients show viral material in plasma, associated with a dysregulated host …