Accumulating evidence shows that deregulation of fatty acid (FA) metabolism is associated
with the development of cancer. Long-chain acyl-coenzyme A synthases (ACSLs) are …

Colorectal cancer (CRC) is a highly aggressive and life-threatening malignancy that
metastasizes in~ 50% of patients, posing significant challenges to patient survival and …

Extibacter muris is a newly described mouse gut bacterium which metabolizes cholic acid
(CA) to deoxycholic acid (DCA) via 7α-dehydroxylation. Although bile acids influence …

Monascus-fermented rice has been used to treat digestive disorder and promote blood
circulation in China and other Asian countries for centuries. However, the effects and …

Five acyl-CoA synthetase long-chain family members (ACSLs) are responsible for catalyzing
diverse long-chain fatty acids (LCFAs) into LCFA-acyl-coenzyme A (CoA) for their …

Ethnopharmacological relevance Hepatocyte lipid accumulation is the main feature in the
early stage of nonalcoholic fatty liver disease (NAFLD). Highland barley Monascus …

This study aimed to investigate the protective mechanism of common buckwheat
(Fagopyrum esculentum Moench.) against nonalcoholic fatty liver disease (NAFLD) …

The molecular mechanism by which lipid/lipoprotein biosynthesis is regulated in mammals
involves a very large number of genes that are subject to multiple levels of regulation …

Dyslipidemia is the primary cause of cardiovascular disease, which is a serious human
health problem in large parts of the world. Therefore, it is important to understand the genetic …

Long-chain acyl-CoA synthetases (Acsls), members of the acyl-activating enzyme
superfamily, haves been systematically characterized in mammals and certain fishes, but the …