Representational drift as a window into neural and behavioural plasticity

C Micou, T O'Leary - Current opinion in neurobiology, 2023 - Elsevier
Large-scale recordings of neural activity over days and weeks have revealed that neural
representations of familiar tasks, precepts and actions continually evolve without obvious …

Time and experience differentially affect distinct aspects of hippocampal representational drift

N Geva, D Deitch, A Rubin, Y Ziv - Neuron, 2023 - cell.com
Hippocampal activity is critical for spatial memory. Within a fixed, familiar environment,
hippocampal codes gradually change over timescales of days to weeks—a phenomenon …

Representational drift in the mouse visual cortex

D Deitch, A Rubin, Y Ziv - Current biology, 2021 - cell.com
Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …

Neural ensembles in navigation: From single cells to population codes

EAA Jones, LM Giocomo - Current opinion in neurobiology, 2023 - Elsevier
The brain can represent behaviorally relevant information through the firing of individual
neurons as well as the coordinated firing of ensembles of neurons. Neurons in the …

Space is a latent sequence: A theory of the hippocampus

RV Raju, JS Guntupalli, G Zhou, C Wendelken… - Science …, 2024 - science.org
Fascinating phenomena such as landmark vector cells and splitter cells are frequently
discovered in the hippocampus. Without a unifying principle, each experiment seemingly …

Hippocampal place codes are gated by behavioral engagement

NL Pettit, XC Yuan, CD Harvey - Nature neuroscience, 2022 - nature.com
As animals explore an environment, the hippocampus is thought to automatically form and
maintain a place code by combining sensory and self-motion signals. Instead, we observed …

Spatial information encoding across multiple neocortical regions depends on an intact hippocampus

IM Esteves, HR Chang, AR Neumann… - Journal of …, 2021 - Soc Neuroscience
There has been considerable research showing populations of neurons encoding for
different aspects of space in the brain. Recently, several studies using two-photon calcium …

[HTML][HTML] Perpetual step-like restructuring of hippocampal circuit dynamics

ZS Zheng, R Huszár, T Hainmueller, M Bartos… - Cell reports, 2024 - cell.com
Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …

Functional network topography of the medial entorhinal cortex

HA Obenhaus, W Zong, RI Jacobsen… - Proceedings of the …, 2022 - National Acad Sciences
The medial entorhinal cortex (MEC) creates a map of local space, based on the firing
patterns of grid, head-direction (HD), border, and object-vector (OV) cells. How these cell …

Organization of hippocampal CA3 into correlated cell assemblies supports a stable spatial code

L Sheintuch, N Geva, D Deitch, A Rubin, Y Ziv - Cell reports, 2023 - cell.com
Hippocampal subfield CA3 is thought to stably store memories in assemblies of recurrently
connected cells functioning as a collective. However, the collective hippocampal coding …