Biofabrication of bone tissue: approaches, challenges and translation for bone regeneration

D Tang, RS Tare, LY Yang, DF Williams, KL Ou… - Biomaterials, 2016 - Elsevier
The rising incidence of bone disorders has resulted in the need for more effective therapies
to meet this demand, exacerbated by an increasing ageing population. Bone tissue …

Vascularization strategies in bone tissue engineering

F Simunovic, G Finkenzeller - Cells, 2021 - mdpi.com
Bone is a highly vascularized tissue, and its development, maturation, remodeling, and
regeneration are dependent on a tight regulation of blood vessel supply. This condition also …

Biomimetic materials and fabrication approaches for bone tissue engineering

HD Kim, S Amirthalingam, SL Kim… - Advanced …, 2017 - Wiley Online Library
Various strategies have been explored to overcome critically sized bone defects via bone
tissue engineering approaches that incorporate biomimetic scaffolds. Biomimetic scaffolds …

Biomimetic approaches in bone tissue engineering: Integrating biological and physicomechanical strategies

MA Fernandez-Yague, SA Abbah, L McNamara… - Advanced drug delivery …, 2015 - Elsevier
The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

Bone tissue engineering

CRM Black, V Goriainov, D Gibbs, J Kanczler… - Current molecular …, 2015 - Springer
Medical advances have led to a welcome increase in life expectancy. However,
accompanying longevity introduces new challenges: increases in age-related diseases and …

Importance of dual delivery systems for bone tissue engineering

M Farokhi, F Mottaghitalab, MA Shokrgozar… - Journal of Controlled …, 2016 - Elsevier
Bone formation is a complex process that requires concerted function of multiple growth
factors. For this, it is essential to design a delivery system with the ability to load multiple …

Multi‐dimensional printing for bone tissue engineering

M Qu, C Wang, X Zhou, A Libanori… - Advanced …, 2021 - Wiley Online Library
The development of 3D printing has significantly advanced the field of bone tissue
engineering by enabling the fabrication of scaffolds that faithfully recapitulate desired …

[HTML][HTML] Surface delivery of tunable doses of BMP-2 from an adaptable polymeric scaffold induces volumetric bone regeneration

M Bouyer, R Guillot, J Lavaud, C Plettinx, C Olivier… - Biomaterials, 2016 - Elsevier
The rapid and effective bone regeneration of large non-healing defects remains challenging.
Bioactive proteins, such as bone morphogenetic protein (BMP)-2, are proved their …

3D liver models on a microplatform: well-defined culture, engineering of liver tissue and liver-on-a-chip

KH Lee, J Lee, SH Lee - Lab on a Chip, 2015 - pubs.rsc.org
The liver, the largest organ in the human body, is a multi-functional organ with diverse
metabolic activities that plays a critical role in maintaining the body and sustaining life …

Recent progress in the manipulation of biochemical and biophysical cues for engineering functional tissues

B Bakhshandeh, N Ranjbar, A Abbasi… - Bioengineering & …, 2023 - Wiley Online Library
Tissue engineering (TE) is currently considered a cutting‐edge discipline that offers the
potential for developing treatments for health conditions that negatively affect the quality of …