GWAS and functional studies suggest a role for altered DNA repair in the evolution of drug resistance in Mycobacterium tuberculosis

S Naz, K Paritosh, P Sanyal, S Khan, Y Singh… - Elife, 2023 - elifesciences.org
The emergence of drug resistance in Mycobacterium tuberculosis (Mtb) is alarming and
demands in-depth knowledge for timely diagnosis. We performed genome-wide association …

Molecular modeling, simulation and docking of Rv1250 protein from Mycobacterium tuberculosis

S Choudhary, AK Kesavan, V Juneja… - Frontiers in …, 2023 - frontiersin.org
Computational prediction and protein structure modeling have come to the aid of various
biological problems in determining the structure of proteins. These technologies have …

Correlations between comorbidities, chest x-ray findings, and C-Reactive protein level in patients with COVID-19

M Fachri, M Hatta, E Widowati, R Akaputra… - Annals of Medicine …, 2022 - journals.lww.com
Background: Patients with comorbidities have an increased risk for severe coronavirus
disease (COVID-19) symptoms, including abnormal inflammation. Chest X-rays and C …

[HTML][HTML] Comparison TLR2 and TLR4 serum levels in children with pulmonary and extrapulmonary tuberculosis with and without a Bacillus Calmette-Guérin (BCG) …

R Shabariah, M Hatta, I Idris, A Santoso… - Journal of Clinical …, 2021 - Elsevier
The formation of a scar after Mycobacterium bovis Bacillus Calmette-Guérin (BCG)
vaccination influences the effectiveness of protection against Mycobacterium tuberculosis …

[HTML][HTML] The effect of miana (coleus scutellariodes [L]) on vascular endothelial growth factor expression in Balb/C mice infected with mycobacterium tuberculosis

R Marlina, M Hatta, E Sridiana… - Biomedical and …, 2021 - biomedpharmajournal.org
Tuberculosis (TB) is still a major global health problem. The increasing prevalence of
antibiotic resistance has posed a major threat towards the mission of TB eradication …

[PDF][PDF] The changes of HIF-1α and ICAM-1 expression after Miana (coleus Scutellariodes [L]) treatment in Balb/C mice with Mycobacterium tuberculosis infection

I Patellongi, AD Susanto, AA Islam… - Biomedical & …, 2022 - pdfs.semanticscholar.org
Increasing resistance to TB drugs raises the challenge of TB eradication. Miana leaves is
Indonesian traditional herbal medicine, have antimicrobial, anti-inflammatory, and …

[HTML][HTML] Molecular characterisation of mutations associated with resistance to first-and second-line drugs among Indonesian patients with tuberculosis

FF Umar, DR Husain, MM Hatta, RR Natzir… - Journal of Taibah …, 2020 - Elsevier
Genetic resistance among groups of bacteria can be caused by transfer of genetic elements
through transduction or transformation. In Mycobacterium tuberculosis (MTBC), genetic …

Identification of Mutations Conferring Tryptanthrin Resistance to Mycobacterium smegmatis

SG Frolova, KM Klimina, R Kumar, AA Vatlin… - Antibiotics, 2020 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a global burden, responsible
for over 1 million deaths annually. The emergence and spread of drug-resistant M …

Heparin for patients with coronavirus disease 2019 and hypercoagulation complications: A cohort study

M Fachri, M Hatta, SNNA Tarigan… - Annals of Medicine …, 2022 - journals.lww.com
Background: Thrombotic complications of coronavirus disease 2019 (COVID-19) are a
worrisome aspect of the disease due to their high incidence in critically ill patients and their …

Overexpression of a membrane transport system MSMEG_1381 and MSMEG_1382 confers multidrug resistance in Mycobacterium smegmatis

S Salini, B Muralikrishnan, SG Bhat, SD Ghate… - Microbial …, 2023 - Elsevier
Mycobacterium tuberculosis is a leading cause of human mortality worldwide, and the
emergence of drug-resistant strains demands the discovery of new classes of …