Effects of early life stress on the developing basolateral amygdala-prefrontal cortex circuit: the emerging role of local inhibition and perineuronal nets
A Guadagno, C Belliveau, N Mechawar… - Frontiers in human …, 2021 - frontiersin.org
The links between early life stress (ELS) and the emergence of psychopathology such as
increased anxiety and depression are now well established, although the specific …
increased anxiety and depression are now well established, although the specific …
Early life adversity shapes social subordination and cell type–specific transcriptomic patterning in the ventral hippocampus
Adverse events in early life can modulate the response to additional stressors later in life
and increase the risk of developing psychiatric disorders. The underlying molecular …
and increase the risk of developing psychiatric disorders. The underlying molecular …
[HTML][HTML] Epigenetic mechanisms impacted by chronic stress across the rodent lifespan
A Dion, PT Muñoz, TB Franklin - Neurobiology of Stress, 2022 - Elsevier
Exposures to stress at all stages of development can lead to long-term behavioural effects,
in part through changes in the epigenome. This review describes rodent research …
in part through changes in the epigenome. This review describes rodent research …
[HTML][HTML] Early life stress impairs synaptic pruning in the developing hippocampus
Early life adversity impairs normal hippocampal function and connectivity in various
mammalian species, including humans and rodents. According to the 'cumulative model'the …
mammalian species, including humans and rodents. According to the 'cumulative model'the …
Sex-specific behavioral and structural alterations caused by early-life stress in C57BL/6 and BTBR mice
VV Reshetnikov, KA Ayriyants, YA Ryabushkina… - Behavioural Brain …, 2021 - Elsevier
Lately, the development of various mental illnesses, such as depression, personality
disorders, and autism spectrum disorders, is often associated with traumatic events in …
disorders, and autism spectrum disorders, is often associated with traumatic events in …
[HTML][HTML] Early life adversity in male mice sculpts reward circuits
Early life adversity (ELA) comprises a wide variety of negative experiences during early life
and has been linked to cognitive impairments, reduced experiences of pleasure …
and has been linked to cognitive impairments, reduced experiences of pleasure …
Distinct stress‐related medial prefrontal cortex activation in women with depression with and without childhood maltreatment
D Dong, EL Belleau, M Ironside, X Zhong… - Depression and …, 2022 - Wiley Online Library
Background Emerging evidence has highlighted the moderating effect of childhood
maltreatment (CM) in shaping neurobiological abnormalities in major depressive disorder …
maltreatment (CM) in shaping neurobiological abnormalities in major depressive disorder …
[HTML][HTML] Towards reliable reconstruction of the mouse brain corticothalamic connectivity using diffusion MRI
Diffusion magnetic resonance imaging (dMRI) tractography has yielded intriguing insights
into brain circuits and their relationship to behavior in response to gene mutations or …
into brain circuits and their relationship to behavior in response to gene mutations or …
Early adversity changes the economic conditions of mouse structural brain network organization
Early adversity can change educational, cognitive, and mental health outcomes. However,
the neural processes through which early adversity exerts these effects remain largely …
the neural processes through which early adversity exerts these effects remain largely …
Points of divergence on a bumpy road: early development of brain and immune threat processing systems following postnatal adversity
HC Brenhouse - Molecular psychiatry, 2023 - nature.com
Lifelong indices of maladaptive behavior or illness often stem from early physiological
aberrations during periods of dynamic development. This is especially true when …
aberrations during periods of dynamic development. This is especially true when …