Mechanisms of osteoarthritis (OA) pain

TW O'Neill, DT Felson - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Osteoarthritis (OA) is a major cause of pain and disability
worldwide. There is, however, a relatively poor correlation between the severity of OA based …

[HTML][HTML] Prevalence of knee osteoarthritis features on magnetic resonance imaging in asymptomatic uninjured adults: a systematic review and meta-analysis

AG Culvenor, BE Øiestad, HF Hart… - British journal of sports …, 2019 - bjsm.bmj.com
Background Knee MRI is increasingly used to inform clinical management. Features
associated with osteoarthritis are often present in asymptomatic uninjured knees; however …

Pathobiology of Modic changes

S Dudli, AJ Fields, D Samartzis, J Karppinen… - European Spine …, 2016 - Springer
Purpose Low back pain (LBP) is the most disabling condition worldwide. Although LBP
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …

Epidemiology of osteoarthritis

Y Zhang, JM Jordan - Clinics in geriatric medicine, 2010 - geriatric.theclinics.com
Osteoarthritis (OA) is the most common joint disorder in the United States. 1 Among adults
60 years of age or older the prevalence of symptomatic knee OA is approximately 10% in …

EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis

W Zhang, M Doherty, G Peat… - Annals of the …, 2010 - ard.bmj.com
Objective To develop evidence-based recommendations for the diagnosis of knee
osteoarthritis (OA). Methods The multidisciplinary guideline development group …

Diagnosis of osteoarthritis: imaging

HJ Braun, GE Gold - Bone, 2012 - Elsevier
Osteoarthritis (OA) is a chronic, debilitating joint disease characterized by degenerative
changes to the bones, cartilage, menisci, ligaments, and synovial tissue. Imaging modalities …

Etiopathogenesis of osteoarthritis

KD Brandt, P Dieppe, EL Radin - Rheumatic Disease Clinics of North …, 2008 - Elsevier
In this article, the authors posit that, because osteoarthritis (OA) involves all of the tissues of
the synovial joint, the emphasis on the loss of cartilage, in particular, is misguided. In …

[HTML][HTML] Peripheral pain mechanisms in osteoarthritis

TL Vincent - Pain, 2020 - journals.lww.com
There is a well-established historical observation that structural joint damage by plain X-ray
correlates poorly with symptomatic disease in osteoarthritis (OA). This is often attributed to …

Osteoarthritis, part of life or a curable disease? A bird's‐eye view

M Englund - Journal of Internal Medicine, 2023 - Wiley Online Library
Osteoarthritis (OA) is a chronic joint disease caused by disruption of joint homeostasis by a
variety of systemic and biomechanical factors. The disease is characterized by degradation …

Association between radiographic features of knee osteoarthritis and pain: results from two cohort studies

T Neogi, D Felson, J Niu, M Nevitt, CE Lewis… - Bmj, 2009 - bmj.com
Objective To examine the relation of radiographic features of osteoarthritis to knee pain in
people with knees discordant for knee pain in two cohorts. Design Within person, knee …