[HTML][HTML] Advancing virtual bioequivalence for orally administered drug products: methodology, real-world applications and future outlook
S Kollipara, FS Martins, R Jereb, D Krajcar, T Ahmed - Pharmaceuticals, 2024 - mdpi.com
Bioequivalence studies are pivotal in generic drug development wherein therapeutic
equivalence is provided with an innovator product. However, bioequivalence studies …
equivalence is provided with an innovator product. However, bioequivalence studies …
[HTML][HTML] Advances in Canine Anesthesia: Physiologically Based Pharmacokinetic Modeling for Predicting Propofol Plasma Profiles in Canines with Hepatic …
LWF Gonzaga, BM Egito, JBC Coelho, GP Souza… - Pharmaceuticals, 2024 - mdpi.com
Background: A PBPK model allows the prediction of the concentration of drug amounts in
different tissues and organs over time and can be used to simulate and optimize different …
different tissues and organs over time and can be used to simulate and optimize different …
Physiologically Based Pharmacokinetic and Physiologically Based Biopharmaceutic models research in Latin America: A regional level bibliometric analysis, 2011 …
M Ribeiro, JC Cardoso, JES Martins… - Brazilian Journal of …, 2025 - SciELO Brasil
The landscape of scientific research in Latin America (LA), particularly in the realms of the
Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic …
Physiologically Based Pharmacokinetic (PBPK) and Physiologically Based Biopharmaceutic …
Linking in vitro–in vivo extrapolations with physiologically based modeling to inform drug and formulation development.
R Cristofoletti… - Biopharmaceutics & Drug …, 2023 - search.ebscohost.com
Quantitative I in vitro-in vivo i extrapolations (IVIVE) have been applied extensively to predict
drug metabolism and transporter kinetics (Sodhi & Benet,[20]; Wood et al.,[22]; Zamek …
drug metabolism and transporter kinetics (Sodhi & Benet,[20]; Wood et al.,[22]; Zamek …