TRPA1: A promising target for pulmonary fibrosis?

C Li, J Xu, A Abdurehim, Q Sun, J Xie… - European Journal of …, 2023 - Elsevier
Pulmonary fibrosis is a disease characterized by progressive scar formation and the ultimate
manifestation of numerous lung diseases. It is known as “cancer that is not cancer” and has …

Atractylodin: An Alkyne Compound with Anticancer Potential

W Zhong, Q Zhang - The American Journal of Chinese Medicine, 2024 - World Scientific
Atractylodin is one of the main active ingredients of Atractylodis Rhizoma. It has various
pharmacological properties, such as antigastric ulcer, immune regulation, antibacterial, anti …

Advanced dynamic weight bearing as an observer-independent measure of hyperacute hypersensitivity in mice

JO Dent, JP Segal, A Brécier, HGM Gowdy… - Canadian Journal of …, 2023 - Taylor & Francis
Background Standard methods assessing pain in rodents are often observer dependent,
potentially resulting in biased outcomes. Advanced dynamic weight bearing (ADWB) offers …

[HTML][HTML] Yokukansan suppresses gastric hypersensitivity and eosinophil-associated microinflammation in rats with functional dyspepsia

S Duan, N Imamura, T Kondo, H Kanda… - Journal of …, 2022 - ncbi.nlm.nih.gov
Methods The MS stress model was established by separating newborn Sprague-Dawley
rats from their mothers for 2 hours a day from postnatal days 1 to 10. At the age of 7-8 weeks …

Scorpion Venom peptide, AGAP inhibits TRPV1 and potentiates the analgesic effect of lidocaine

S Kampo, Y Cui, J Yu, TW Anabah, AA Falagán… - Heliyon, 2021 - cell.com
The current study was designed to test the hypothesis that BmK AGAP (AGAP) potentiates
the analgesic effect of lidocaine. The chronic constrictive injury was performed on 72 rats to …

Atractylodin mitigates UVB radiation-induced oxidative stress and photoaging responses by enhancing NrF2 signaling in human epidermal keratinocytes

F Gao, Y Sun, H Gan - Archives of Dermatological Research, 2024 - Springer
This study explores the protective role of Atractylodin (ATN) on ultraviolet-B (UVB) radiation-
exposed oxidative damage and photoaging responses in human epidermal keratinocytes …

Linalyl acetate exerts analgesic effects by inhibiting nociceptive TRPA1 in mice

M Hashimoto, K Takahashi, T Unno, T Ohta - Biomedical Research, 2024 - jstage.jst.go.jp
Clary sage essential oil (CSEO) is utilized in perfumery, aromatherapy, and skincare. Linalyl
acetate (LA), a primary component of CSEO, possesses sedative, anxiolytic, and analgesic …

鞘内注射瞬时受体电位通道A1 shRNA 对部分坐骨神经结扎小鼠神经病理性疼痛的作用及其机制

赵峰, 樊少卿, 程晓燕, 李小娜, 李长生… - 吉林大学学报(医学 …, 2021 - xuebao.jlu.edu.cn
目的: 探讨瞬时受体电位通道A1 (TRPA1) 在部分坐骨神经结扎(pSNL) 小鼠神经病理性疼痛模型
中的作用, 阐明其作用机制. 方法: 30 只SPF 级雄性C57BL/6 小鼠随机分为对照组(n= 6) …

漢方薬の鎮痛作用におけるTRP チャネルの関与

戴毅 - PAIN RESEARCH, 2021 - jstage.jst.go.jp
抄録 Transient receptor potential (TRP) ion channels form a family of ligand–gated ion
channels that function as molecular detectors of physical stimuli, including light …