An approach to measuring colistin plasma levels regarding the treatment of multidrug-resistant bacterial infection

T Pacheco, RH Bustos, D González, V Garzón… - Antibiotics, 2019 - mdpi.com
Antimicrobial resistance to antibiotic treatment has significantly increased during recent
years, causing this to become a worldwide public health problem. More than 70% of …

Targeted Delivery of Antibiotic Therapy to Inhibit Pseudomonas aeruginosa Using Lipid-Coated Mesoporous Silica Core–Shell Nanoassembly

K Rathnayake, U Patel, C Pham, A McAlpin… - ACS applied bio …, 2020 - ACS Publications
Pseudomonas aeruginosa (PA) is an opportunistic pathogen, which causes serious lung
infections in immunocompromised patients. Traditional oral intake of large quantities of …

Analytical methodologies for measuring colistin levels in pharmacokinetic studies

MS Zabidi, R Abu Bakar, N Musa… - Journal of Liquid …, 2020 - Taylor & Francis
Colistin is an old antibiotic reintroduced in response to an increased incidence of multi-
resistant Gram-negative bacterial infections. It has a narrow therapeutic window, and dose …

Colistimethate sodium-chitosan hydrogel for treating gram-negative bacterial wound infections

A Pradeep, N Ashok, V Priya, AV Pillai… - International Journal of …, 2022 - Elsevier
The drug resistance is higher among Gram-negative bacteria and demands the usage of
strong antibiotics which can in turn result in systemic toxicity. In the treatment of the chronic …

Synthesis of Novel Antibacterial and Biocompatible Colistin-Loaded Cellulose/Manganese Oxide Nanocomposite Hydrogel Film

F Kazeminava, S Beheshti, N Monavari, R Afkari… - Journal of Polymers and …, 2024 - Springer
This study aims to design an innovative flexible nanocomposite film via the integration of
MnO2 NPs into the biopolymeric carboxymethyl cellulose (CMC) hydrogel for improving its …

[PDF][PDF] Pre-study on radiolabeling of colistin with Lutetium-177 to develop theranostic infection agent

M Karpuz, E Ozgenc, E Atlihan-Gundogdu, Z Burak - J Res Pharm, 2022 - researchgate.net
Infection is one of the important burdens on the health care system, not only due to leading
morbidity and mortality but also because of the development of antibiotic resistance …

Estimation of the Difference in Colistin Plasma Levels in Critically Ill Patients with Favorable or Unfavorable Clinical Outcomes

J Sanabria, V Garzón, T Pacheco, MP Avila, JC Garcia… - Pharmaceutics, 2021 - mdpi.com
In recent decades, antimicrobial resistance (AMR) has led to an increased use of therapeutic
alternatives. Among these options, colistin continues to be an option for the treatment of …