American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment of deep vein thrombosis and pulmonary embolism

TL Ortel, I Neumann, W Ageno, R Beyth… - Blood …, 2020 - ashpublications.org
In August 2022, these guidelines were reviewed by an expert work group convened by ASH.
Review included limited searches for new evidence and discussion of the search results …

A test in context: D-dimer

JI Weitz, JC Fredenburgh, JW Eikelboom - Journal of the American College …, 2017 - jacc.org
D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

Deep vein thrombosis and pulmonary embolism

M Di Nisio, N van Es, HR Büller - The Lancet, 2016 - thelancet.com
Deep vein thrombosis and pulmonary embolism, collectively referred to as venous
thromboembolism, constitute a major global burden of disease. The diagnostic work-up of …

Comparison between different D‐D imer cutoff values to assess the individual risk of recurrent venous thromboembolism: analysis of results obtained in the DULCIS …

G Palareti, C Legnani, B Cosmi… - International Journal …, 2016 - Wiley Online Library
Introduction D‐dimer assay, generally evaluated according to cutoff points calibrated for VTE
exclusion, is used to estimate the individual risk of recurrence after a first idiopathic event of …

Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice …

C Kearon, EA Akl, AJ Comerota, P Prandoni… - Chest, 2012 - Elsevier
Background This article addresses the treatment of VTE disease. Methods We generated
strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A) …

Review of D‐dimer testing: Good, Bad, and Ugly

LA Linkins, S Takach Lapner - International Journal of …, 2017 - Wiley Online Library
D‐dimer assays are commonly used in clinical practice to exclude a diagnosis of deep vein
thrombosis or pulmonary embolism. More recently, they have been also been used to guide …

D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications

J Favresse, G Lippi, PM Roy, B Chatelain… - Critical reviews in …, 2018 - Taylor & Francis
D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …

Prediction of venous thromboembolism in cancer patients

C Ay, D Dunkler, C Marosi, AL Chiriac… - Blood, The Journal …, 2010 - ashpublications.org
The risk of venous thromboembolism (VTE) is increased in cancer patients. To improve
prediction of VTE in cancer patients, we performed a prospective and observational cohort …

Epidemiology of venous thromboembolism

JA Heit - Nature Reviews Cardiology, 2015 - nature.com
Thrombosis can affect any venous circulation. Venous thromboembolism (VTE) includes
deep-vein thrombosis of the leg or pelvis, and its complication, pulmonary embolism. VTE is …

The epidemiology of venous thromboembolism

JA Heit, FA Spencer, RH White - Journal of thrombosis and thrombolysis, 2016 - Springer
Venous thromboembolism (VTE) is categorized by the US Surgeon General as a major
public health problem. VTE is relatively common and associated with reduced survival and …