A review of biomarkers and their clinical impact in resected early-stage non-small-cell lung cancer

W Cao, Q Tang, J Zeng, X Jin, L Zu, S Xu - Cancers, 2023 - mdpi.com
Simple Summary Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of
all lung cancers, and the postoperative survival of early-stage NSCLC patients remains …

History, molecular features, and clinical importance of conventional serum biomarkers in lung cancer

H Nakamura, T Nishimura - Surgery Today, 2017 - Springer
Serum biomarkers provide valuable information about the diagnosis and prognosis of a
wide variety of malignant tumors. Despite the identification of several useful serum …

Prognostic value of blood-based protein biomarkers in non-small cell lung cancer: A critical review and 2008–2022 update

I Trulson, S Holdenrieder - Tumor Biology, 2024 - journals.sagepub.com
BACKGROUND: Therapeutic possibilities for non-small cell lung cancer (NSCLC) have
considerably increased during recent decades. OBJECTIVE: To summarize the prognostic …

The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in …

L Zhang, D Liu, L Li, D Pu, P Zhou, Y Jing, H Yu… - BMC cancer, 2017 - Springer
Background The roles of carcinoembryonic antigen (CEA), cytokeratin 19 fragments
(CYFRA21-1) and neuron-specific enolase (NSE) in metastases occurrence and poor …

Oncologic outcomes of surgery versus sbrt for non–small-cell lung carcinoma: a systematic review and meta-analysis

MA Ijsseldijk, M Shoni, C Siegert, B Wiering… - Clinical Lung Cancer, 2021 - Elsevier
Background The optimal treatment of stage I non–small-cell lung carcinoma is subject to
debate. The aim of this study was to compare overall survival and oncologic outcomes of …

Proteomics biomarkers for non-small cell lung cancer

J Kisluk, M Ciborowski, M Niemira, A Kretowski… - … of pharmaceutical and …, 2014 - Elsevier
In the last decade, proteomic analysis has become an integral tool for investigation of tumor
biology, complementing the genetic analysis. The idea of proteomics is to characterize …

Prognostic impact of serum CYFRA 21–1 in patients with advanced lung adenocarcinoma: a retrospective study

A Ono, T Takahashi, K Mori, H Akamatsu, T Shukuya… - BMC cancer, 2013 - Springer
Background Serum CYFRA 21–1 is one of the most important serum markers in the
diagnosis of non-small cell lung cancer (NSCLC), especially squamous-cell carcinoma …

Prognostic value of serum cytokeratin 19 fragments (Cyfra 21-1) in patients with non-small cell lung cancer

Y Xu, L Xu, M Qiu, J Wang, Q Zhou, L Xu, J Wang… - Scientific reports, 2015 - nature.com
The role of serum CYFRA 21-1 level in patients with non-small cell lung cancer (NSCLC)
remains to be defined. To re-evaluate the impact of serum CYFRA 21-1 in NSCLC survival …

[HTML][HTML] A combination of radiomic features, imaging characteristics, and serum tumor biomarkers to predict the possibility of the high-grade subtypes of lung …

Y Liu, Y Chang, X Zha, J Bao, Q Wu, H Dai, C Hu - Academic Radiology, 2022 - Elsevier
Rationale and Objectives Lung adenocarcinomas (LADC) containing high-grade subtypes
have a poorer prognosis. And some studies have shown that high-grade subtypes have …

[HTML][HTML] Prognostic significance of KRT19 in lung squamous cancer

X Yuan, M Yi, B Dong, Q Chu, K Wu - Journal of Cancer, 2021 - ncbi.nlm.nih.gov
Abstract Backgroud: Keratin 19 (KRT19) is the intermediate filament that constitutes the
cytoskeleton and regulates cell-cycle and cell death. Objective: We aimed to assess whether …