Tissue fibrosis is a pathological condition that is associated with impaired epithelial repair
and excessive deposition of extracellular matrix (ECM). Fibrotic lesions increase the risk of …

Transcriptional enhanced associate domain (TEAD) transcription factors play important roles
during development, cell proliferation, regeneration, and tissue homeostasis. TEAD …

Colorectal cancer (CRC) is the third most frequently detected type of cancer, and the second
most common cause of cancer-related mortality globally. The American Cancer Society …

Triboelectric nanogenerators have garnered significant attention as alternative power
sources for wearable electronics owing to their simple structure, easy fabrication, low cost …

Background: Conversion of cardiac stromal cells into myofibroblasts is typically associated
with hypoxia conditions, metabolic insults, and/or inflammation, all of which are predisposing …

Simple Summary The canonical WNT/β-catenin pathway is upregulated in cancers and
plays a major role in proliferation, invasion, apoptosis and angiogenesis. Recent studies …

The Hippo pathway is a crucial signaling mechanism that inhibits the growth of cells and
organs during development and in disease. When the Hippo pathway is activated, YAP/TAZ …

The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

Cells that lack p53 signaling frequently occur in ulcerative colitis (UC) and are considered
early drivers in UC-associated colorectal cancer (CRC). Epithelial injury during colitis is …

Skin is the largest organ of the human body. Its architecture and physiological functions
depend on diverse populations of epidermal cells and dermal fibroblasts. Reciprocal …