Cancer stem cells (CSCs) in cancer progression and therapy

M Najafi, B Farhood… - Journal of cellular …, 2019 - Wiley Online Library
Cancer stem cells (CSCs) are self‐renewable cell types that are identified in most types of
liquid and solid cancers and contributed to tumor onset, expansion, resistance, recurrence …

[HTML][HTML] Brain malignancies: Glioblastoma and brain metastases

TT Lah, M Novak, B Breznik - Seminars in cancer biology, 2020 - Elsevier
Brain, the major organ of the central nervous system controls and processes most of body
activities. Therefore, the most aggressive brain tumor–glioblastoma and metastases from …

WNT signaling in tumors: the way to evade drugs and immunity

E Martin-Orozco, A Sanchez-Fernandez… - Frontiers in …, 2019 - frontiersin.org
WNT/β-catenin signaling is involved in many physiological processes. Its implication in
embryonic development, cell migration, and polarization has been shown. Nevertheless …

Cancer stem cell-targeted bio-imaging and chemotherapeutic perspective

J Han, M Won, JH Kim, E Jung, K Min… - Chemical Society …, 2020 - pubs.rsc.org
Cancer stem cells (CSCs), also called tumor-initiating cells (TICs), have been studied
intensively due to their rapid proliferation, migration, and role in the recurrence of cancer. In …

Design, synthesis, and SAR studies of novel 4-methoxyphenyl pyrazole and pyrimidine derivatives as potential dual tyrosine kinase inhibitors targeting both EGFR …

AM El-Naggar, AMA Hassan, EB Elkaeed… - Bioorganic …, 2022 - Elsevier
Guided by the pharmacophoric features of both EGFR and VEGFR-2 antagonists, two novel
series of 4-methoxyphenyl pyrazole and pyrimidine derivatives [(4a-c) and (5a-c, 6, 7a-c, 8 …

Dissecting tumor growth: the role of cancer stem cells in drug resistance and recurrence

B Aramini, V Masciale, G Grisendi, F Bertolini, M Maur… - Cancers, 2022 - mdpi.com
Simple Summary Cancer is one of the most debated problems all over the world. Cancer
stem cells are considered responsible of tumor initiation, metastasis, drug resistance, and …

Macrophage-cancer hybrid membrane-coated nanoparticles for targeting lung metastasis in breast cancer therapy

C Gong, X Yu, B You, Y Wu, R Wang, L Han… - Journal of …, 2020 - Springer
Cell membrane-covered drug-delivery nanoplatforms have been garnering attention
because of their enhanced bio-interfacing capabilities that originate from source cells. In this …

Characterization of stem cell landscape and identification of stemness-relevant prognostic gene signature to aid immunotherapy in colorectal cancer

H Zheng, H Liu, H Li, W Dou, J Wang, J Zhang… - Stem cell research & …, 2022 - Springer
Background It is generally accepted that colorectal cancer (CRC) originates from cancer
stem cells (CSCs), which are responsible for CRC progression, metastasis and therapy …

Ferroptosis: cancer stem cells rely on iron until “to die for” it

E Cosialls, R El Hage, L Dos Santos, C Gong… - Cells, 2021 - mdpi.com
Cancer stem cells (CSCs) are a distinct subpopulation of tumor cells with stem cell-like
features. Able to initiate and sustain tumor growth and mostly resistant to anti-cancer …

Nanotreatment and nanodiagnosis of prostate cancer: recent updates

M Barani, F Sabir, A Rahdar, R Arshad, GZ Kyzas - Nanomaterials, 2020 - mdpi.com
The fabrication and development of nanomaterials for the treatment of prostate cancer have
gained significant appraisal in recent years. Advancements in synthesis of organic and …