Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the developing fetus. Multiple microbes …

Acute chorioamnionitis is characterized by neutrophilic infiltration and inflammation at the
maternal fetal interface. It is a relatively common complication of pregnancy and can have …

Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has caused over 12 million infections and more than 550 000 deaths. 1 Morbidity and …

Preterm labor commonly precedes preterm birth, the leading cause of perinatal morbidity
and mortality worldwide. Most research has focused on establishing a causal link between …

Reproduction involves tightly regulated series of events and the immune system is involved
in an array of reproductive processes. Disruption of well-controlled immune functions leads …

Survivors of preterm birth struggle with multitudes of disabilities due to improper in utero
programming of various tissues and organ systems contributing to adult-onset diseases at a …

Diabetic hyperglycemia aggravates the prognosis of intracerebral hemorrhagic stroke (ICH)
in the clinic. In addition to hematoma expansion and increased inflammation, how diabetic …

Preterm birth is the leading cause of neonatal morbidity and mortality worldwide. One of
every 4 preterm neonates is born to a mother with intra-amniotic inflammation driven by …

Preterm birth (PTB) remains the leading cause of infant morbidity and mortality. Despite 50
years of research, therapeutic options are limited and many lack clear efficacy. Tocolytic …

Blockade of the interleukin-1 (IL-1) pathway has been used therapeutically in several
inflammatory diseases including arthritis and cryopyrin-associated periodic syndrome …