A CK2 and SUMO-dependent, PML NB-involved regulatory mechanism controlling BLM ubiquitination and G-quadruplex resolution

S Liu, E Atkinson, A Paulucci-Holthauzen… - Nature …, 2023 - nature.com
The Boom syndrome helicase (BLM) unwinds a variety of DNA structures such as Guanine
(G)-quadruplex. Here we reveal a role of RNF111/Arkadia and its paralog ARKL1, as well as …

Protein Kinase CK2 and Epstein–Barr Virus

M Montenarh, FA Grässer, C Götz - Biomedicines, 2023 - mdpi.com
Protein kinase CK2 is a pleiotropic protein kinase, which phosphorylates a number of
cellular and viral proteins. Thereby, this kinase is implicated in the regulation of cellular …

The ARK2N–CK2 complex initiates transcription-coupled repair through enhancing the interaction of CSB with lesion-stalled RNAPII

Y Luo, J Li, X Li, H Lin, Z Mao, Z Xu… - Proceedings of the …, 2024 - National Acad Sciences
Transcription is extremely important for cellular processes but can be hindered by RNA
polymerase II (RNAPII) pausing and stalling. Cockayne syndrome protein B (CSB) promotes …

G1/S Cell Cycle Induction by Epstein-Barr Virus BORF2 Is Mediated by P53 and APOBEC3B

J Yockteng-Melgar, K Shire, AZ Cheng… - Journal of …, 2022 - Am Soc Microbiol
Herpesvirus lytic infection causes cells to arrest at the G1/S phase of the cell cycle by poorly
defined mechanisms. In a prior study using fluorescent ubiquitination-based cell cycle …

A primary nasopharyngeal three-dimensional air-liquid interface cell culture model of the pseudostratified epithelium reveals differential donor-and cell type-specific …

P Ziegler, Y Tian, Y Bai, S Abrahamsson… - PLoS …, 2021 - journals.plos.org
Epstein-Barr virus (EBV) is a ubiquitous γ-herpesvirus with latent and lytic cycles. EBV
replicates in the stratified epithelium but the nasopharynx is also composed of …

Determining the Significance of BORF2 Interaction With A3B and p53 in EBV Infection

JDY Melgar - 2023 - search.proquest.com
Epstein-Barr virus (EBV) is a human herpesvirus that infects over 90% of the world's
population and is a causative agent of several types of cancers. EBV establishes lifelong …