[HTML][HTML] Mitochondrial malfunction mediates impaired cholinergic Ca2+ signalling and submandibular salivary gland dysfunction in diabetes

O Kopach, T Pivneva, N Fedirko, N Voitenko - Neuropharmacology, 2024 - Elsevier
Xerostomia (dry-mouth syndrome) is a painful and debilitating condition that frequently
occurs in individuals with diabetes and is associated with impaired saliva production and …

[HTML][HTML] Metformin-induced activation of Ca2+ signaling prevents immune infiltration/pathology in Sjogren's syndrome-prone mouse models

VN Da Conceicao, Y Sun, X Chai, JL Ambrus… - Journal of Translational …, 2023 - Elsevier
Immune cell infiltration and glandular dysfunction are the hallmarks of autoimmune diseases
such as primary Sjogren's syndrome (pSS), however, the mechanism (s) is unknown. Our …

Pathophysiological Role of TRPC1 in Cell Function

EM Martínez, HL Ong, IS Ambudkar - TRP-Mediated Signaling - taylorfrancis.com
TRPC1 was first identified almost three decades ago as a store-operated calcium (Ca2+)
channel mediating extracellular Ca2+ entry in response to ER-Ca2+ store depletion. TRPC1 …

[引用][C] Journal of Translational Autoimmunity

VN Da Conceicao, Y Sun, X Chai… - Journal of …, 2023 - europepmc.org
Immune cell infiltration and glandular dysfunction are the hallmarks of autoimmune diseases
such as primary Sjogren's syndrome (pSS), however, the mechanism (s) is unknown. Our …