[HTML][HTML] Recent changes in patterns of mammal infection with highly pathogenic avian influenza A (H5N1) virus worldwide
PI Plaza, V Gamarra-Toledo, JR Euguí… - Emerging Infectious …, 2024 - ncbi.nlm.nih.gov
We reviewed information about mammals naturally infected by highly pathogenic avian
influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020–2023) and …
influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020–2023) and …
Reverse zoonosis of influenza to swine: new perspectives on the human–animal interface
MI Nelson, AL Vincent - Trends in microbiology, 2015 - cell.com
The origins of the 2009 influenza A (H1N1) pandemic in swine are unknown, highlighting
gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how …
gaps in our understanding of influenza A virus (IAV) ecology and evolution. We review how …
Swine influenza virus: Current status and challenge
W Ma - Virus research, 2020 - Elsevier
Since swine influenza virus was first isolated in 1930, it has become endemic in pigs
worldwide. Although large amount of swine influenza vaccines has been used in swine …
worldwide. Although large amount of swine influenza vaccines has been used in swine …
[HTML][HTML] Low susceptibility of pigs against experimental infection with HPAI virus H5N1 clade 2.3. 4.4 b
A Graaf, R Piesche, J Sehl-Ewert, C Grund… - Emerging Infectious …, 2023 - ncbi.nlm.nih.gov
We found that nasal and alimentary experimental exposure of pigs to highly pathogenic
avian influenza virus H5N1 clade 2.3. 4.4 b was associated with marginal viral replication …
avian influenza virus H5N1 clade 2.3. 4.4 b was associated with marginal viral replication …
H5N1 infection impairs the alveolar epithelial barrier through intercellular junction proteins via Itch-mediated proteasomal degradation
T Ruan, Y Sun, J Zhang, J Sun, W Liu, RA Prinz… - Communications …, 2022 - nature.com
The H5N1 subtype of the avian influenza virus causes sporadic but fatal infections in
humans. H5N1 virus infection leads to the disruption of the alveolar epithelial barrier, a …
humans. H5N1 virus infection leads to the disruption of the alveolar epithelial barrier, a …
A systematic review analyzing the prevalence and circulation of influenza viruses in swine population worldwide
RP Chauhan, ML Gordon - Pathogens, 2020 - mdpi.com
The global anxiety and a significant threat to public health due to the current COVID-19
pandemic reiterate the need for active surveillance for the zoonotic virus diseases of …
pandemic reiterate the need for active surveillance for the zoonotic virus diseases of …
In vitro and in vivo antiviral activity of gingerenone a on influenza a virus is mediated by targeting janus kinase 2
J Wang, RA Prinz, X Liu, X Xu - Viruses, 2020 - mdpi.com
Janus kinase (JAK) inhibitors have been developed as novel immunomodulatory drugs and
primarily used for treating rheumatoid arthritis and other inflammatory diseases. Recent …
primarily used for treating rheumatoid arthritis and other inflammatory diseases. Recent …
[HTML][HTML] Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication
J Zhang, T Ruan, T Sheng, J Wang, J Sun, J Wang… - Virology, 2019 - Elsevier
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially
regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying …
regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying …
Deciphering transmission dynamics and spillover of avian influenza viruses from avian species to swine populations globally
RP Chauhan, ML Gordon - Virus Genes, 2021 - Springer
Genome sequences of eleven avian influenza virus (AIV) subtypes have been reported in
swine populations from seven countries until August 2020. To unravel the transmission …
swine populations from seven countries until August 2020. To unravel the transmission …
A77 1726, the active metabolite of the anti‐rheumatoid arthritis drug leflunomide, inhibits influenza A virus replication in vitro and in vivo by inhibiting the activity of …
J Wang, J Sun, J Hu, C Wang, RA Prinz… - The FASEB …, 2020 - Wiley Online Library
The newly reassorted IAV subtypes from zoonotic reservoirs respond poorly to current
vaccines and antiviral therapy. There is an unmet need in developing novel antiviral drugs …
vaccines and antiviral therapy. There is an unmet need in developing novel antiviral drugs …