Treatment opportunities with Fernandoa adenophylla and recent novel approaches for natural medicinal phytochemicals as a drug delivery system

SK Mall, T Yadav, A Waziri, MS Alam - Exploration of Medicine, 2022 - explorationpub.com
Fernandoa adenophylla (FA, Heterophragma adenophyllum) is a plant, cultivated
throughout Africa and Southeast Asia. It contains potent phytochemicals such as novel …

Density functional theory, molecular docking, In vitro and In vivo anti-inflammatory investigation of lapachol isolated from Fernandoa adenophylla

A Rauf, TS AlOmar, S Sarfaraz, K Ayub, F Hussain… - Heliyon, 2023 - cell.com
Medicinal plants are the main source of active chemical constituents responsible for curing
or mitigating various ailments. To discover new, safe, and effective drug candidates the …

Anti-inflammatory and anti-diabetic properties of indanone derivative isolated from Fernandoa adenophylla in vitro and in silico studies

A Rauf, U Rashid, ZA Shah, AA Khalil, M Shah… - Scientific Reports, 2024 - nature.com
Fernandoa adenophylla, due to the presence of phytochemicals, has various beneficial
properties and is used in folk medicine to treat many conditions. This study aimed to isolate …

In Vivo and In Vitro Biological Evaluation and Molecular Docking Studies of Compounds Isolated from Micromeria biflora (Buch. Ham. ex D.Don) Benth

ASM Aljohani, FA Alhumaydhi, A Rauf, EM Hamad… - Molecules, 2022 - mdpi.com
Micromeria biflora, a traditional medicinal plant, is extensively used for treating various
painful conditions, such as nose bleeds, wounds, and sinusitis. A phytochemical …

Quality characteristics, phytochemical analysis, and antioxidant of extract Cuscuta reflexa (Roxb.)

AR Sidhu, A Basit, A Hayat, S Mangrio… - Notulae Botanicae …, 2022 - notulaebotanicae.ro
Cuscuta reflexa is an extensive leafless, parasitic climber that has been used since ancient
times for various purposes and as a therapeutic plant in different areas of Pakistan. The …

Total synthesis of peshawaraquinone through late-stage [3+ 2] cycloaddition or α-ketol rearrangement

H Guo, L Ren, X Sang, X Lu, T Li, W Zhou… - Organic Chemistry …, 2024 - pubs.rsc.org
Two synthetic approaches to peshawaraquinone, an uncommon and complex
naphthoquinone meroterpenoid, are described. Key to the success of these synthetic …

[HTML][HTML] Evaluation of the anti-diarrheal effects of the whole plant extracts of Cuscuta reflexa Roxb in pigeons

N Muhammad, S Ullah, A Rauf, M Atif, S Patel, M Israr… - Toxicology Reports, 2021 - Elsevier
Background Cuscuta reflexa (dodder) belonging to the family Convolvulaceae has many
ethno-medicinal uses such as antidiarrheal and antiemetic. This plant has been employed to …

Molecular docking, DFT studies, and anti-inflammatory evaluation of peshawaraquinone isolated from Fernandoa adenophylla

T S. AlOmar, A Rauf, U Rashid, S Sarfaraz… - Journal of …, 2024 - Taylor & Francis
In recent years, there has been growing interest in exploring natural compounds with anti-
inflammatory properties for potential therapeutic applications. This study focuses on …

Aldose reductase inhibitory evaluation and in silico studies of bioactive secondary metabolites isolated from Fernandoa. adenophylla (Wall. ex G. Don)

A Rauf, S Naz, MU Khan, T Zahid, Z Ahmad… - Journal of Molecular …, 2025 - Elsevier
Diabetes and its associated secondary complications represent significant global health
challenges. This study aimed to address these issues by investigating Fernandoa …

[HTML][HTML] Potent urease inhibition and in silico docking study of four secondary metabolites isolated from Heterophragma adenophyllum Seem

A Rauf, YS Al-Awthan, O Bahattab, ZA Shah… - South African Journal of …, 2021 - Elsevier
To isolate four phytochemicals (Lapachol, Peshawarquinone-a novel Naphthoquinone,
Indanone derivatives and Lapachone), from the methanolic fraction of Heterophragma …