Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide.
Until now, treatments for depression have focused on the inhibition of monoaminergic …

The hippocampus plays an important role in emotional and cognitive processing, and both
of these domains are affected in patients with major depressive disorder (MDD). Extensive …

It is unclear how binding of antidepressant drugs to their targets gives rise to the clinical
antidepressant effect. We discovered that the transmembrane domain of tyrosine kinase …

Cognitive processes, particularly learning and memory, are crucial brain mechanisms
mediating the successful adaptation of individuals to constantly changing environmental …

The serotonergic system is involved in diverse cognitive functions including memory. Of
particular importance to daily life are declarative memories that contain information about …

Dysregulation of hippocampal neurogenesis is linked to several neurodegenereative
diseases, where boosting hippocampal neurogenesis in these patients emerges as a …

Different brain regions' interactions have been implicated in relevant neurological diseases,
such as major depressive disorder (MDD), anxiety disorders, age-dependent cognitive …

A need for new therapeutic approaches are necessary for dementia conditions and memory
deficits of different origins, such as Alzheimer's disease. There is complex …

Background: Clinically depressed individuals respond to different types of antidepressants,
suggesting that different neurobiological mechanisms may be responsible for their …

Post-stroke depression, observed in 30-50% of stroke patients, negatively affects quality of
life and mortality. The pathogenesis of post-stroke depression is complex, but heightened …