The tumor burden score: a new “metro-ticket” prognostic tool for colorectal liver metastases based on tumor size and number of tumors

K Sasaki, D Morioka, S Conci, GA Margonis… - Annals of …, 2018 - journals.lww.com
Objective: To apply the principles of the Metro-ticket paradigm to develop a prognostic
model for patients undergoing hepatic resection of colorectal liver metastasis (CRLM) …

[HTML][HTML] Surgery for colorectal liver metastases: The evolution of determining prognosis

G Spolverato, A Ejaz, N Azad… - World journal of …, 2013 - ncbi.nlm.nih.gov
Despite improvements in the multi-modality treatment of colorectal liver metastasis (CRLM),
survival after resection remains varied. Determining prognosis after surgical resection has …

Pathological factors and prognosis of resected liver metastases of colorectal carcinoma: implications and proposal for a pathological reporting protocol

GM Fonseca, P Herman, SF Faraj, JAP Kruger… - …, 2018 - Wiley Online Library
Colorectal cancer is a leading cause of death worldwide. The liver is the most common site
of distant metastases, and surgery is the only potentially curative treatment, although the …

[HTML][HTML] Synchronous and metachronous liver metastases in patients with colorectal cancer—towards a clinically relevant definition

J Engstrand, C Strömberg, H Nilsson… - World journal of surgical …, 2019 - Springer
Background Approximately 25% of patients with colorectal cancer (CRC) will have liver
metastases classified as synchronous or metachronous. There is no consensus on the …

Prognostic factors change over time after hepatectomy for colorectal liver metastases: a multi-institutional, international analysis of 1099 patients

GA Margonis, S Buettner, N Andreatos… - Annals of …, 2019 - journals.lww.com
Objective: To evaluate the changing impact of genetic and clinicopathologic factors on
conditional overall survival (CS) over time in patients with resectable colorectal liver …

Combined hepatic resection and radio-frequency ablation for patients with colorectal cancer liver metastasis: a viable option for patients with a large number of tumors

T Masuda, GA Margonis, N Andreatos… - Anticancer …, 2018 - ar.iiarjournals.org
Background/Aim: Radiofrequency ablation (RFA) is thought to result in inferior prognosis
than hepatic resection among patients with colorectal liver metastasis (CRLM). However …

[HTML][HTML] Predicting metachronous liver metastasis in patients with colorectal cancer: development and assessment of a new nomogram

M Hao, H Li, K Wang, Y Liu, X Liang, L Ding - World journal of surgical …, 2022 - Springer
Background We aimed to develop and validate a nomogram model, which could predict
metachronous liver metastasis in colorectal cancer within two years after diagnosis. Methods …

Higher tumor burden neutralizes negative margin status in hepatectomy for colorectal cancer liver metastasis

M Oshi, GA Margonis, Y Sawada, N Andreatos… - Annals of surgical …, 2019 - Springer
Objective The aim of this study was to examine if the prognostic significance of margin status
in hepatectomy for colorectal cancer liver metastasis (CRLM) varies for different levels of …

The preoperative lymphocyte-to-monocyte ratio is prognostic of clinical outcomes for patients with liver-only colorectal metastases in the neoadjuvant setting

K Neofytou, EC Smyth, A Giakoustidis, AZ Khan… - Annals of surgical …, 2015 - Springer
Background Circulating monocyte-derived, tumor-associated macrophages are associated
with a poor prognosis for various cancers. Conversely, circulating lymphocytes are the …

Different variables predict the outcome of patients with synchronous versus metachronous metastases of colorectal cancer

GA Colloca, A Venturino, D Guarneri - Clinical and Translational Oncology, 2020 - Springer
Purpose Timing of metastasis is a controversial prognostic factor for patients with metastatic
colorectal cancer (mCRC), as well as the performance of the common prognostic variables …