[HTML][HTML] Comprehensive evaluation of recombinant lactate dehydrogenase production from inclusion bodies

CL Igwe, JN Pauk, DF Müller, M Jaeger… - Journal of …, 2024 - Elsevier
A broad application spectrum ranging from clinical diagnostics to biosensors in a variety of
sectors, makes the enzyme Lactate dehydrogenase (LDH) highly interesting for recombinant …

Recombinant production, purification, and biochemical characterization of a novel L-lactate dehydrogenase from Bacillus cereus NRC1 and inhibition study of …

SS Esa, AF El-Sayed, MI El-Khonezy… - … in Bioengineering and …, 2023 - frontiersin.org
Lactate dehydrogenase (LDH, EC 1.1. 1.27) is one of the vital glycolytic conditions,
especially during anaerobic conditions. It is a significant diagnostic, prognostic, and …

Purification and partial biochemical characterization of recombinant lactate dehydrogenase 1 (LDH-1) of the white shrimp Litopenaeus vannamei

L Leyva-Carrillo, M Hernandez-Palomares… - Protein Expression and …, 2019 - Elsevier
Lactate dehydrogenase (LDH) is a key enzyme to produce energy during hypoxia by
anaerobic glycolysis. In the white shrimp Litopenaeus vannamei, two protein subunits (LDH …

Strong epistasis constrains the evolution of strict substrate specificity in apicomplexan lactate dehydrogenases

JD Wirth, JI Boucher, C Xu, S Classen, DL Theobald - bioRxiv, 2023 - biorxiv.org
The homologous enzymes lactate and malate dehydrogenase (L/MDH) are structurally
similar but are specific for different substrates. LDH vs MDH specificity is canonically …

Evaluation of parasite proteins in diagnosis

TG İnci - acikbilim.yok.gov.tr
Plasmodium vivax and Theileria annulata are apicomplexan parasites which affects human
and cattle, respectively, and cause morbidity and mortality. Especially Plasmodium lactate …

Functional Convergence and Epistasis in Apicomplexan Lactate Dehydrogenases

JDS Wirth - 2019 - search.proquest.com
Enzyme structures and functions evolve over time, but how changes occur is often
unexplained. How do enzymes evolve new functions? How many mutations did it take to …

Functional and structural characterization of the pentapeptide insertion of Theileria annulata lactate dehydrogenase by site-directed mutagenesis, comparative …

A Erdemir, O Mutlu - Journal of Molecular Graphics and Modelling, 2017 - Elsevier
Lactate dehydrogenase (LDH) is an important metabolic enzyme in glycolysis and it has
been considered as the main energy source in many organisms including apicomplexan …

Genetic engineering of Theileria parva lactate dehydrogenase gene: a new anti-theilerial target

I Icen-Taskin, O Munzuroglu, H Geckil - Pesquisa Veterinária …, 2018 - SciELO Brasil
Theileria parva is the causative agent of East Coast Fever (ECF), a tick borne disease, which
results in major economic losses in cattle. Major problems in dealing with this illness are the …