Oncolytic viruses (OVs) are emerging as potentially useful platforms in treatment methods for
patients with tumors. They preferentially target and kill tumor cells, leaving healthy cells …

The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

Oncolytic viruses have been taking the front stage in biological therapy for cancer recently.
The first and most potent virus to be used in oncolytic virotherapy is human adenovirus …

Oncolytic viruses (OVs) infect, multiply, and finally remove tumor cells selectively, causing no
damage to normal cells in the process. Because of their specific features, such as, the ability …

Chimeric antigen receptor T cell (CAR-T cell) therapy is a novel adoptive immunotherapy
where T lymphocytes are engineered with synthetic receptors known as chimeric antigen …

Interaction of spherical particles with cells and within animals has been studied extensively,
but the effects of shape have received little attention. Here we use highly stable, polymer …

Oncolytic viruses (OVs) as one promising antitumor methods have made important
contributions to tumor immunotherapy, which arouse increasing attention. They provide the …

Although viruses are most often studied as pathogens, many are beneficial to their hosts,
providing essential functions in some cases and conditionally beneficial functions in others …

The clinical efficacy of chimeric antigen receptor (CAR)-redirected T cells remains marginal
in solid tumors compared with leukemias. Failures have been attributed to insufficient T-cell …

The efficacy and safety of biological molecules in cancer therapy, such as peptides and
small interfering RNAs (siRNAs), could be markedly increased if high concentrations could …