Emerging biology of noncoding RNAs in malaria parasites
In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …
Noncoding RNAs in apicomplexan parasites: an update
Recent breakthroughs in high-throughput technologies, transcriptomics, and advances in
our understanding of gene regulatory networks have enhanced our perspective on the …
our understanding of gene regulatory networks have enhanced our perspective on the …
Novel insights into the role of long non-coding RNA in the human malaria parasite, Plasmodium falciparum
G Batugedara, XM Lu, B Hristov, S Abel… - Nature …, 2023 - nature.com
The complex life cycle of Plasmodium falciparum requires coordinated gene expression
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …
regulation to allow host cell invasion, transmission, and immune evasion. Increasing …
Ectopic overexpression of Plasmodium falciparum DNA-/RNA-binding Alba proteins misregulates virulence gene homeostasis during asexual blood development
D Acharya, AN Bavikatte, VV Ashok… - Microbiology …, 2025 - journals.asm.org
Alba domain-containing proteins are ubiquitously found in archaea and eukaryotes. By
binding to either DNA, RNA, or DNA: RNA hybrids, these proteins function in genome …
binding to either DNA, RNA, or DNA: RNA hybrids, these proteins function in genome …
The PfAlba1 RNA-binding protein is an important regulator of translational timing in Plasmodium falciparum blood stages
SS Vembar, CR Macpherson, O Sismeiro, JY Coppée… - Genome biology, 2015 - Springer
Background Transcriptome-wide ribosome occupancy studies have suggested that during
the intra-erythrocytic lifecycle of Plasmodium falciparum, select mRNAs are post …
the intra-erythrocytic lifecycle of Plasmodium falciparum, select mRNAs are post …
Landscape and dynamics of transcription initiation in the malaria parasite Plasmodium falciparum
A comprehensive map of transcription start sites (TSSs) across the highly AT-rich genome of
P. falciparum would aid progress toward deciphering the molecular mechanisms that …
P. falciparum would aid progress toward deciphering the molecular mechanisms that …
Recent advances in malaria genomics and epigenomics
Malaria continues to impose a significant disease burden on low-and middle-income
countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid …
countries in the tropics. However, revolutionary progress over the last 3 years in nucleic acid …
Trans-acting GC-rich non-coding RNA at var expression site modulates gene counting in malaria parasite
J Guizetti, A Barcons-Simon, A Scherf - Nucleic acids research, 2016 - academic.oup.com
Monoallelic expression of the var multigene family enables immune evasion of the malaria
parasite Plasmodium falciparum in its human host. At a given time only a single member of …
parasite Plasmodium falciparum in its human host. At a given time only a single member of …
[HTML][HTML] Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression
Highlights•Small and long noncoding RNAs are abundant in Plasmodium falciparum blood
stages.•Subtelomeric and intronic ncRNAs may determine singular var gene choice.•Natural …
stages.•Subtelomeric and intronic ncRNAs may determine singular var gene choice.•Natural …
[HTML][HTML] Characterization of P. vivax blood stage transcriptomes from field isolates reveals similarities among infections and complex gene isoforms
Our understanding of the structure and regulation of Plasmodium vivax genes is limited by
our inability to grow the parasites in long-term in vitro cultures. Most P. vivax studies must …
our inability to grow the parasites in long-term in vitro cultures. Most P. vivax studies must …