The Safety of bacteriophages in Treatment of diseases caused by Multidrug-Resistant Bacteria

KM Chung, SC Nang, SS Tang - Pharmaceuticals, 2023 - mdpi.com
Given the urgency due to the rapid emergence of multidrug-resistant (MDR) bacteria,
bacteriophages (phages), which are viruses that specifically target and kill bacteria, are …

High activity and specificity of bacteriophage cocktails against carbapenem-resistant Klebsiella pneumoniae belonging to the high-risk clones CG258 and ST307

S Tellez-Carrasquilla, L Salazar-Ospina… - Frontiers in …, 2024 - frontiersin.org
Introduction The widespread clinical and environmental dissemination of successful clones
of carbapenem-resistant Klebsiella pneumoniae (CRKP) represents a serious global public …

Characterization and complete genome analysis of a bacteriophage vB_EcoM_DE7 infecting donkey-derived Escherichia coli

J Cui, W Liu, Y Zang, C Zhang, L Zou, H Sun, Q Pan… - Virus Research, 2022 - Elsevier
A lytic bacteriophage vB_EcoM_DE7 (hereafter designated DE7) that could infect donkey-
derived Escherichia coli was isolated. The bacteriophage was examined by transmission …

Preclinical characterization and in silico safety assessment of three virulent bacteriophages targeting carbapenem-resistant uropathogenic Escherichia coli

G Dhungana, R Nepal, G Houtak, G Bouras… - International …, 2024 - Springer
Phage therapy has recently been revitalized in the West with many successful applications
against multi-drug-resistant bacterial infections. However, the lack of geographically diverse …

New Bacteriophages Members of the Ackermannviridae Family Specific for Klebsiella pneumoniae ST258

E Tisalema-Guanopatín, F Cabezas-Mera… - PHAGE, 2023 - liebertpub.com
Background: Carbapenem-resistant Klebsiella pneumoniae, particularly isolates classified
as sequence-type 258 (ST258), are multidrug-resistant strains that are strongly associated …

Genomic characterization of three bacteriophages infecting donkey-derived Escherichia coli

JQ Cui, WH Liu, C Zhang, L Zou, HY Ren - Virus Genes, 2023 - Springer
Bacteriophages are an important source of novel genetic diversity. Sequencing of phage
genomes can reveal new proteins with potential uses in phage therapy and help unravel the …

The Importance of Klebsiella pneumoniae as a Pathogen and the Increasing Prevalence of Antibiotic-Resistant Strains and Molecular Characteristics

W Mohammed, FA Awad, TI Mustafa - Baghdad Journal of Biochemistry …, 2023 - bjbabs.org
Klebsiella pneumoniae is a significant pathogen causing various infections, and antibiotic-
resistant strains of K. pneumoniae are becoming more prevalent. Molecular studies reveal …

Prevalence and Pattern of Antibiotic Susceptibility of Gram-Negative Bacteria Isolated from Pediatric Blood Culture

E Turan, M Bayraktar, B Ibrahım - Mehmet Akif Ersoy University …, 2024 - dergipark.org.tr
It was aimed to evaluate the antibiotic susceptibilities of Gram-negative bacteria isolated
from blood samples taken from pediatric patients. The samples were evaluated with the …

Characterization and preclinical in silico safety assessment of three virulent bacteriophages targeting carbapenem-resistant uropathogenic Escherichia coli

G Dhungana, R Nepal, G Houtak, GS Bouras… - 2023 - preprints.org
Escherichia coli causes several infections like intestinal diarrhea, urinary tract infections,
and pneumonia, which are difficult to treat due to the emergence of antimicrobial resistance …