Ocular chemical injuries vary in severity, with the more severe end of the spectrum having
profound visual consequences and medicolegal implications. Grading of ocular injuries is …

Chemical eye injury (CEI) is an acute emergency which can threaten sight and life. These
commonly occur at home or the workplace with the former being generally mild and the latter …

Corneal alkali burn (AB) injury is the most common sight-threatening injury that is highly
associated with oxidative stress, inflammation, apoptosis, angiogenesis, and cell deficiency …

Millions of people worldwide are bilaterally blind due to corneal diseases including
infectious etiologies, trauma, and chemical injuries. While corneal transplantation can …

Purpose: To evaluate the efficacy of losartan and prednisolone acetate in inhibiting corneal
scarring fibrosis after alkali burn injury in rabbits. Methods: Sixteen New Zealand White …

Alkali burn-induced corneal inflammation and subsequent corneal neovascularization
(CNV) are major causes of corneal opacity and vision loss. M1 macrophages play a central …

Chemical injuries to the eye are emergencies with limited acute treatment options other than
prompt irrigation and can cause permanent vision loss. We developed a perfluorodecalin …

Age-related macular degeneration (AMD) is a leading cause of blindness worldwide. Early
to intermediate AMD is characterized by the accumulation of lipid-and protein-rich drusen …

Previous studies have demonstrated that ocular injury can lead to prompt infiltration of bone-
marrow–derived peripheral monocytes into the retina. However, the ability of these cells to …

Eyes that have experienced alkali burn to the surface are excessively susceptible to
subsequent severe glaucoma and retinal ganglion cell loss, despite maximal efforts to …