Intrinsically different retinal progenitor cells produce specific types of progeny

C Cepko - Nature Reviews Neuroscience, 2014 - nature.com
Lineage studies conducted in the retina more than 25 years ago demonstrated the
multipotency of retinal progenitor cells (RPCs). The number and types of cells produced by …

Temporal fate specification and neural progenitor competence during development

M Kohwi, CQ Doe - Nature Reviews Neuroscience, 2013 - nature.com
The vast diversity of neurons and glia of the CNS is generated from a small, heterogeneous
population of progenitors that undergo transcriptional changes during development to …

Cell fate determination in the vertebrate retina.

CL Cepko, CP Austin, X Yang… - Proceedings of the …, 1996 - National Acad Sciences
In the vertebrate central nervous system, the retina has been a useful model for studies of
cell fate determination. Recent results from studies conducted in vitro and in vivo suggest a …

Use of type I collagen green fluorescent protein transgenes to identify subpopulations of cells at different stages of the osteoblast lineage

I Kalajzic, Z Kalajzic, M Kaliterna… - Journal of Bone and …, 2002 - academic.oup.com
Green fluorescent protein (GFP)‐expressing transgenic mice were produced containing a
3.6‐kilobase (kb; pOBCol3. 6GFPtpz) and a 2.3‐kb (pOBCol2. 3GFPemd) rat type I collagen …

How variable clones build an invariant retina

J He, G Zhang, AD Almeida, M Cayouette, BD Simons… - Neuron, 2012 - cell.com
A fundamental question in developmental neuroscience is how a collection of progenitor
cells proliferates and differentiates to create a brain of the appropriate size and cellular …

[HTML][HTML] Cellular resolution maps of X chromosome inactivation: implications for neural development, function, and disease

H Wu, J Luo, H Yu, A Rattner, A Mo, Y Wang… - Neuron, 2014 - cell.com
Female eutherian mammals use X chromosome inactivation (XCI) to epigenetically regulate
gene expression from∼ 4% of the genome. To quantitatively map the topography of XCI for …

Neural crest cell contribution to the developing circulatory system: implications for vascular morphology?

M Bergwerff, ME Verberne, MC DeRuiter… - Circulation …, 1998 - Am Heart Assoc
In this study, the distribution patterns of neural crest (NC) cells (NCCs) in the developing
vascular system of the chick were thoroughly studied and examined for a correlation with …

NeuroD regulates multiple functions in the developing neural retina in rodent

EM Morrow, T Furukawa, JE Lee, CL Cepko - Development, 1999 - journals.biologists.com
The expression and function of the basic helix-loop-helix (bHLH) transcription factor NeuroD
were studied in the developing neural retina in rodent. neuroD was expressed in areas of …

Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch

CP Austin, DE Feldman, JA Ida Jr, CL Cepko - Development, 1995 - journals.biologists.com
The first cells generated during development of the vertebrate retina are the ganglion cells,
the projection neurons of the retina. Although they are one of the most intensively studied …

The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates

CL Cepko - Current opinion in neurobiology, 1999 - Elsevier
A fundamental issue concerning development of the vertebrate retina is the relative
contributions of extrinsic and intrinsic cues to the determination of cell fate. Recent findings …