From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2024 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

[HTML][HTML] CircRNAs: Pivotal modulators of TGF-β signalling in cancer pathogenesis

AA Bhat, G Gupta, R Dahiya, R Thapa, A Gahtori… - Non-coding RNA …, 2024 - Elsevier
The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

Exosomal ncRNAs in liquid biopsies for lung cancer

MS Hussain, G Gupta, N Ghaboura, E Moglad… - Clinica chimica acta, 2024 - Elsevier
Exosomal non-coding RNAs (ncRNAs) have become essential contributors to advancing
and treating lung cancers (LCs). The development of liquid biopsies that utilize exosomal …

Polyphenol-loaded nano-carriers for breast cancer therapy: a comprehensive review

AA Bhat, G Gupta, M Afzal, R Thapa, H Ali… - BioNanoScience, 2024 - Springer
Breast cancer remains a significant global health challenge, demanding innovative
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …

Role of mitochondria in inflammatory lung diseases

VR Narala, SR Narala, P Aiya Subramani… - Frontiers in …, 2024 - frontiersin.org
Mitochondria play a significant and varied role in inflammatory lung disorders. Mitochondria,
known as the powerhouse of the cell because of their role in producing energy, are now …

Deciphering NF-kappaB pathways in smoking-related lung carcinogenesis

R Thapa, E Moglad, A Goyal, AA Bhat… - EXCLI …, 2024 - pmc.ncbi.nlm.nih.gov
One of the main causes of death worldwide is lung cancer, which is largely caused by
cigarette smoking. The crucial transcription factor NF-κB, which controls inflammatory …

GAS5: A pivotal lncRNA in diabetes mellitus pathogenesis and management

KS Alharbi - Pathology-Research and Practice, 2024 - Elsevier
The long non-coding RNA (lncRNA), GAS5, has garnered significant attention recently for its
multifaceted involvement in cellular processes, particularly within the context of diabetes …

[HTML][HTML] The impact of formaldehyde exposure on lung inflammatory disorders: Insights into asthma, bronchitis, and pulmonary fibrosis

AA Bhat, M Afzal, A Goyal, G Gupta, R Thapa… - Chemico-biological …, 2024 - Elsevier
Lung inflammatory disorders are a major global health burden, impacting millions of people
and raising rates of morbidity and death across many demographic groups. An industrial …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

ncRNAs and Their Impact on Dopaminergic Neurons: Autophagy Pathways in Parkinson's Disease

R Thapa, E Moglad, M Afzal, G Gupta, AA Bhat… - Ageing Research …, 2024 - Elsevier
Parkinson's Disease (PD) is a complex neurological illness that causes severe motor and
non-motor symptoms due to a gradual loss of dopaminergic neurons in the substantia nigra …