Long noncoding RNA and cancer: a new paradigm

A Bhan, M Soleimani, SS Mandal - Cancer research, 2017 - AACR
In addition to mutations or aberrant expression in the protein-coding genes, mutations and
misregulation of noncoding RNAs, in particular long noncoding RNAs (lncRNA), appear to …

[HTML][HTML] Reducing anastomotic leak in colorectal surgery: The old dogmas and the new challenges

J Meyer, S Naiken, N Christou, E Liot… - World journal of …, 2019 - ncbi.nlm.nih.gov
Anastomotic leak (AL) constitutes a significant issue in colorectal surgery, and its incidence
has remained stable over the last years. The use of intra-abdominal drain or the use of …

LncRNAs with miRNAs in regulation of gastric, liver, and colorectal cancers: updates in recent years

C Tam, JH Wong, SKW Tsui, T Zuo, TF Chan… - Applied microbiology and …, 2019 - Springer
Long noncoding RNA (lncRNA) is a kind of RNAi molecule composed of hundreds to
thousands of nucleotides. There are several major types of functional lncRNAs which …

[HTML][HTML] Diagnostic and prognostic potential of tissue and circulating long non-coding RNAs in colorectal tumors

O Galamb, BK Barták, A Kalmár, ZB Nagy… - World journal of …, 2019 - ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are members of the non-protein coding RNA family
longer than 200 nucleotides. They participate in the regulation of gene and protein …

Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 …

Q Li, C Dong, J Cui, Y Wang, X Hong - Journal of Experimental & Clinical …, 2018 - Springer
Background Glioblastoma multiforme (GBM) is the common primary brain tumor classified
the most malignant glioma. Long non-coding RNAs (LncRNAs) are important epigenetic …

Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci

PP Amaral, T Leonardi, N Han, E Viré, DK Gascoigne… - Genome biology, 2018 - Springer
Background The mammalian genome is transcribed into large numbers of long noncoding
RNAs (lncRNAs), but the definition of functional lncRNA groups has proven difficult, partly …

Non-coding RNAs: long non-coding RNAs and microRNAs in endocrine-related cancers

CM Klinge - Endocrine-related cancer, 2018 - erc.bioscientifica.com
The human genome is 'pervasively transcribed'leading to a complex array of non-coding
RNAs (ncRNAs) that far outnumber coding mRNAs. ncRNAs have regulatory roles in …

Non-coding RNAs and glioma: Focus on cancer stem cells

A Rajabi, M Kayedi, S Rahimi, F Dashti… - Molecular Therapy …, 2022 - cell.com
Glioblastoma and gliomas can have a wide range of histopathologic subtypes. These
heterogeneous histologic phenotypes originate from tumor cells with the distinct functions of …

Long non‐coding RNA FOXP 4‐AS 1 is an unfavourable prognostic factor and regulates proliferation and apoptosis in colorectal cancer

J Li, Y Lian, C Yan, Z Cai, J Ding, Z Ma, P Peng… - Cell …, 2017 - Wiley Online Library
Objectives Despite improvements in diagnosis and treatment, colorectal cancer (CRC)
remains the third most common malignancy, and fourth‐leading cause of cancer‐related …

[HTML][HTML] Downregulation of long noncoding RNA HOTAIRM1 variant 1 contributes to osteoarthritis via regulating miR-125b/BMPR2 axis and activating JNK/MAPK/ERK …

Y Xiao, X Yan, Y Yang, X Ma - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Objective: Osteoarthritis (OA) is a leading cause of pain and disability worldwide, which is
characterized by degenerative and inflammatory processes affecting joints and surrounding …