With rapid aging of the population worldwide, the number of people with dementia is
dramatically increasing. Some studies have emphasized that metabolic syndrome, which …

The amygdala was highlighted as an early site for neurofibrillary tau tangle pathology in
Alzheimer's disease in the seminal 1991 article by Braak and Braak. This knowledge has …

Neuroinflammation driven by interferon‐gamma (IFN‐γ) and microglial activation has been
linked to neurological disease. However, the effects of IFN‐γ‐activated microglia on …

Background The natural compound asperosaponin VI has shown potential as an
antidepressant, but how it works is unclear. Here, we explored its effects on mice exposed to …

Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-NF) is a
prospective tool to enhance the emotion regulation capability of participants and to alleviate …

Problematic alcohol drinking and alcohol dependence are an increasing health problem
worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the …

Post-stroke chronic stress (PSCS) is generally associated with the poorer recovery and more
pronounced cognitive dysfunction. Recent evidence has implied that S-ketamine can reduce …

We described behavioral studies to highlight emotional processing deficits in Alzheimer's
disease (AD). The findings suggest prominent deficit in recognizing negative emotions …

Background The ability to understand emotions is often disturbed in patients with cognitive
impairments. Right temporal lobe structures play a crucial role in emotional processing …

Background Physical exercise is known to improve the level of activities of daily living and
physical function in people with dementia; however, symptoms of dementia often pose …