Hfq is an RNA-binding protein that is common to diverse bacterial lineages and has key
roles in the control of gene expression. By facilitating the pairing of small RNAs with their …

The σS (RpoS) subunit of RNA polymerase is the master regulator of the general stress
response in Escherichia coli and related bacteria. While rapidly growing cells contain very …

RyhB is a small antisense regulatory RNA that is repressed by the Fur repressor and
negatively regulates at least six mRNAs encoding Fe-binding or Fe-storage proteins in …

A burgeoning list of small RNAs with a variety of regulatory functions has been identified in
both prokaryotic and eukaryotic cells. However, it remains difficult to identify small RNAs by …

Recent advances in high-throughput pyrosequencing (HTPS) technology now allow a
thorough analysis of RNA bound to cellular proteins, and, therefore, of post-transcriptional …

The bacterial Hfq protein modulates the stability or the translation of mRNAs and has
recently been shown to interact with small regulatory RNAs in E. coli. Here we show that Hfq …

Bacterial small regulatory RNAs (sRNAs) are commonly known to repress gene expression
by base pairing to target mRNAs. In many cases, sRNAs base pair with and sequester …

Hfq, a bacterial member of the Sm family of RNA‐binding proteins, is required for the action
of many small regulatory RNAs that act by basepairing with target mRNAs. Hfq binds this …

The OmpA outer membrane protein of Escherichia coli and other enterobacteria is a
multifaceted protein. This protein is expressed to very high levels and ompA is tightly …

In prokaryotes, Hfq regulates translation by modulating the structure of numerous RNA
molecules by binding preferentially to A/U‐rich sequences. To elucidate the mechanisms of …