Obesity is characterized by increased adipose tissue mass and has been associated with a
strong predisposition towards metabolic diseases and cancer. Thus, it constitutes a public …

The manner in which white adipose tissue (WAT) expands and remodels directly impacts the
risk of developing metabolic syndrome in obesity. Preferential accumulation of visceral WAT …

Adipose tissue depots can exist in close association with other organs, where they assume
diverse, often non-traditional functions. In stem cell-rich skin, bone marrow, and mammary …

Fibrosis disrupts adipose tissue (AT) homeostasis and exacerbates metabolic dysfunction
upon chronic caloric excess. The molecular mechanisms linking adipocyte plasticity to AT …

Understanding adipogenesis, the process of adipocyte development, may provide new ways
to treat obesity and related metabolic diseases. Adipogenesis is controlled by coordinated …

Obesity increases the risks of developing cardiovascular and metabolic diseases and
degrades quality of life, ultimately increasing the risk of death. However, not all forms of …

During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

During development, the human fetus accrues the highest proportion of fat of all mammals.
Precursors of fat lobules can be found at week 14 of pregnancy. Thereafter, they expand …

Adipose tissue undergoes thermogenic remodeling in response to thermal stress and
metabolic cues, playing a crucial role in regulating energy expenditure and metabolic …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …