Proteins, which are ubiquitous in cells and critical to almost all cellular functions, are
indispensable for life. Fluorescence imaging of proteins is key to understanding their …

The GLP-1 receptor, one of the most successful drug targets for the treatment of type 2
diabetes and obesity, is known to engage multiple intracellular signaling proteins. However …

Super-resolution microscopy (SRM) has transformed our understanding of proteins'
subcellular organization and revealed cellular details down to nanometers, far beyond …

Abstract Glucagon-like peptide-1 receptor (GLP1R) and glucose-dependent insulinotropic
polypeptide receptor (GIPR) are transmembrane receptors involved in insulin, glucagon and …

Specific labeling of proteins using membrane-permeable fluorescent probes is a powerful
technique for bioimaging. Cationic fluorescent dyes with high fluorescence quantum yield …

Inflammation is a dynamic process which importantly involves migration of immune cells.
Understanding the onset, acute phase and resolution of inflammation is greatly facilitated by …

Post-labelling cleavable substrates for self-labelling protein tags, such as SNAP-and Halo-
tags, can be used to study cell surface receptor trafficking events by stripping dyes from non …

The glucagon-like peptide-1 receptor (GLP-1R) is a class BG protein–coupled receptor
involved in the regulation of blood glucose levels and food intake. Stabilized agonists …

Synaptic function is governed by highly regulated protein machineries, whose abundance
and spatial localization change continually. Studies to determine the dynamic changes in …

Abstract Glucagon-like peptide-1 receptor (GLP-1R) agonists (GLP-1RAs) are a highly
effective therapy class for type 2 diabetes (T2D) and obesity, yet there are variable patient …