Optimized antimicrobial peptide jelleine-I derivative Br-JI inhibits fusobacterium nucleatum to suppress colorectal cancer progression

F Jia, Q Yu, R Wang, L Zhao, F Yuan, H Guo… - International Journal of …, 2023 - mdpi.com
Colorectal cancer (CRC) is a major health burden worldwide due to its high morbidity,
mortality, and complex etiology. Fusobacterium nucleatum (Fn), a Gram-negative anaerobe …

Optimization of Docetaxel Loading Conditions in Liposomes: Proposing potential products for metastatic breast carcinoma chemotherapy

R Vakili-Ghartavol, SM Rezayat, R Faridi-Majidi… - Scientific reports, 2020 - nature.com
Docetaxel (DTX) was loaded in nanoliposomes based on a new remote loading method
using mannitol and acetic acid as hydration buffer. DTX loading conditions were optimized …

Effects of cLFchimera peptide on intestinal morphology, integrity, microbiota, and immune cells in broiler chickens challenged with necrotic enteritis

A Daneshmand, H Kermanshahi, MH Sekhavati… - Scientific Reports, 2020 - nature.com
Three hundred and sixty 1-day-old male broiler chicks were randomly allocated to 4
treatments of 6 replicates to evaluate the effects of cLFchimera, a recombinant antimicrobial …

Antimicrobial peptide, cLF36, affects performance and intestinal morphology, microflora, junctional proteins, and immune cells in broilers challenged with E. coli

A Daneshmand, H Kermanshahi, MH Sekhavati… - Scientific reports, 2019 - nature.com
This study investigated the effects of an antimicrobial peptide (AMP), cLF36, on growth
performance and the histophysiological changes of the intestine in E. coli-challenged broiler …

Antimicrobial activity of some plant essential oils and an antimicrobial-peptide against some clinically isolated pathogens

A Tanhaeian, MH Sekhavati, M Moghaddam - Chemical and Biological …, 2020 - Springer
Background Essential oils and antimicrobial peptides are two well-known safe and natural
products that have been considered as alternatives to antibiotics. In the present study, the …

A Review on cLF36, a Novel Recombinant Antimicrobial Peptide-Derived Camel Lactoferrin

S Morovati, AA Baghkheirati, MH Sekhavati… - Probiotics and …, 2024 - Springer
Lactoferrin is an antimicrobial peptide (AMP) playing a pivotal role in numerous biological
processes. The primary antimicrobial efficacy of lactoferrin is associated with its N-terminal …

Generation of an engineered food-grade Lactococcus lactis strain for production of an antimicrobial peptide: in vitro and in silico evaluation

A Tanhaeian, M Mirzaii, Z Pirkhezranian… - BMC …, 2020 - Springer
Background Foodborne pathogens and their biofilms are considered as one of the most
serious problems in human health and food industry. Moreover, safety of foods is a main …

A novel chimeric anti-HCV peptide derived from camel lactoferrin and molecular level insight on its interaction with E2

M Tahmoorespur, M Azghandi, A Javadmanesh… - International Journal of …, 2020 - Springer
In the present study, a novel chimeric peptide was derived from camel lactoferrin designed
with a considerable anti-HCV activity and its neutralization mechanism was predicted by …

Computational peptide engineering approach for selection the best engendered camel Lactoferrin-derive peptide with potency to interact with DNA

Z Pirkhezranian, M Tahmoorespur, H Monhemi… - International Journal of …, 2020 - Springer
Antimicrobial peptides (AMPs) are native and safe short peptides with valuable biological
effects. Nowadays, these components and their importance have attracted the attention of …

Expression of Enterocin-P in HEK platform: evaluation of its cytotoxic effects on cancer cell lines and its potency to interact with cell-surface glycosaminoglycan by …

Z Pirkhezranian, A Tanhaeian, M Mirzaii… - International Journal of …, 2020 - Springer
Cancer remains one of the leading causes of death worldwide. Introduction of natural
compounds with anticancer properties can be an effective step in the prevention and …