NEGATIVE ION MASS SPECTROMETRY FOR THE ANALYSIS OF N‐LINKED GLYCANS

DJ Harvey - Mass Spectrometry Reviews, 2020 - Wiley Online Library
N‐glycans from glycoproteins are complex, branched structures whose structural
determination presents many analytical problems. Mass spectrometry, usually conducted in …

Separation of Isomeric O-Glycans by Ion Mobility and Liquid Chromatography–Mass Spectrometry

C Jin, DJ Harvey, WB Struwe, NG Karlsson - Analytical chemistry, 2019 - ACS Publications
Glycosylation is one of the most important post-translational modifications essential for
modulating biological functions on cellular surfaces and within cells. Glycan structures are …

Ion‐mobility spectrometry can assign exact fucosyl positions in glycans and prevent misinterpretation of mass‐spectrometry data after gas‐phase rearrangement

J Sastre Toraño, IA Gagarinov, GM Vos… - Angewandte Chemie …, 2019 - Wiley Online Library
The fucosylation of glycans leads to diverse structures and is associated with many
biological and disease processes. The exact determination of fucoside positions by tandem …

Gas-Phase Internal Ribose Residue Loss from Mg-ATP and Mg-ADP Complexes: Experimental and Theoretical Evidence for Phosphate-Mg-Adenine Interaction

M Franska, O Stezycka, W Jankowski… - Journal of the …, 2022 - ACS Publications
Gas-phase decompositions of magnesium complexes with adenosine-5′-triphosphate
(ATP) and adenosine-5′-diphosphate (ADP) were studied by using electrospray ionization …

Effects of size and geographical origin on Atlantic salmon, Salmo salar, Mucin O-Glycan Repertoire*[S]

J Benktander, V Venkatakrishnan, JT Padra… - Molecular & cellular …, 2019 - ASBMB
Diseases cause ethical concerns and economic losses in the Salmonid industry. The mucus
layer comprised of highly O-glycosylated mucins is the first contact between pathogens and …

In-depth characterization of N-linked oligosaccharides using fluoride-mediated negative ion microfluidic chip LC–MS

W Ni, J Bones, BL Karger - Analytical chemistry, 2013 - ACS Publications
Characterization of N-glycans by liquid chromatography–positive electrospray ionization
(ESI) tandem mass spectrometry (LC–MS/MS) using a microfluidic chip packed with porous …

Various sulfated carbohydrate tumor marker candidates identified by focused glycomic analyses

M Tanaka-Okamoto, M Mukai, H Takahashi… - …, 2017 - academic.oup.com
Glycomic analysis focused on sulfated O-glycans was performed to identify novel serum
carbohydrate tumor markers. Sulfated glycans were enriched by α-neuraminidase digestion …

Presence of terminal N-acetylgalactosamineβ1-4 N-acetylglucosamine residues on O-linked oligosaccharides from gastric MUC5AC: involvement in helicobacter …

DT Kenny, EC Skoog, SK Lindén, WB Struwe… - …, 2012 - academic.oup.com
Isolation of MUC5AC mucins from the gastric mucosa from two secretor individuals (one
from normal mucosa from a patient with gastric cancer and one from a control) showed …

Selected reaction monitoring to differentiate and relatively quantitate isomers of sulfated and unsulfated core 1 O-glycans from salivary MUC7 protein in rheumatoid …

SA Flowers, L Ali, CS Lane, M Olin… - Molecular & Cellular …, 2013 - ASBMB
Rheumatoid arthritis is a common and debilitating systemic inflammatory condition affecting
up to 1% of the world's population. This study aimed to investigate the immunological …

Characterization of glycan structures of chondroitin sulfate-glycopeptides facilitated by sodium ion-pairing and positive mode LC-MS/MS

J Nilsson, F Noborn, A Gomez Toledo… - Journal of The …, 2016 - ACS Publications
Purification and liquid chromatography-tandem mass spectrometry (LC-MS/MS)
characterization of glycopeptides, originating from protease digests of glycoproteins …