The successful treatment of cancer has significantly improved as a result of targeted therapy
and immunotherapy. However, during chemotherapy, cancer cells evolve and can acquire …

Mitochondria serves a primary role in energy maintenance but also function to govern levels
of mitochondria-derived reactive oxygen species (mROS). ROS have long been established …

Low levels of reactive oxygen species (ROS) are crucial for maintaining cancer stem cells
(CSCs) and their ability to resist therapy, but the ROS regulatory mechanisms in CSCs …

Reactive oxygen species (ROS) and their products are components of cell signaling
pathways and play important roles in cellular physiology and pathophysiology. Under …

Abstract Elevated levels of Reactive Oxygen Species (ROS), increased antioxidant ability
and the maintenance of redox homeostasis can cumulatively contribute to tumor progression …

Oncogene‐induced hyper‐proliferation in cancer cells is accompanied by the onset of
different stresses, including DNA‐replication stress, metabolic stress and oxidative stress …

Mitochondria are multifunctional cellular organelles that are major producers of reactive
oxygen species (ROS) in eukaryotes; to maintain the redox balance, they are supplemented …

Peroxiredoxins (PRDXs) are antioxidant enzymes, known to catalyze peroxide reduction to
balance cellular hydrogen peroxide (H 2 O 2) levels, which are essential for cell signaling …

Reactive oxygen species (ROS) are chemically active free radicals produced by partial
reduction of oxygen that can activate discrete signaling pathways or disrupt redox …

Life on Earth evolved in the presence of hydrogen peroxide, and other peroxides also
emerged before and with the rise of aerobic metabolism. They were considered only as toxic …